Page values for "Loperamide"
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"Medicines" values
1 row is stored for this page| Field | Field type | Value |
|---|---|---|
| generic | String | Loperamide |
| brand | String | Imodium, Imodium A-D |
| structure | File | |
| classes | List of String, delimiter: , | [[:Category:Antidiarrheals|Antidiarrheal]] • [[:Category:Opioid_receptor_agonists|Peripheral opioid receptor agonist (μ-selective • gut-restricted)]] |
| mechanism | String | |
| uses | String | '"`UNIQ--vote-00000FCF-QINU`"', '"`UNIQ--vote-00000FD0-QINU`"', '"`UNIQ--vote-00000FD1-QINU`"' |
| starting_dose | String | 4 mg PO initially, then 2 mg after each loose stool, '''not to exceed 16 mg/d''' (8 mg OTC); chronic-use lower |
| preparations | String | 2 mg capsules and tablets; 1 mg/5 mL oral solution; combined with simethicone (Imodium Multi-Symptom) |
| fda_max | String | 16 mg/d (8 mg/d OTC) |
| pill_id | Text | |
| routes | List of String, delimiter: , | Oral |
| onset | String | 30-60 minutes |
| duration | String | 8-12 hours |
| halflife | String | ~9-14 hours'"`UNIQ--ref-00000FD2-QINU`"' |
| bioavailability | String | ~0.3% (oral; extensive first-pass via CYP3A4 and P-glycoprotein-mediated efflux at the intestinal and blood-brain barriers limit systemic and CNS exposure at therapeutic doses)'"`UNIQ--ref-00000FD3-QINU`"' |
| pregnancy | String | Generally considered acceptable when needed.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> |
| legal | String | OTC in US |