Page values for "Nifedipine"
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"Medicines" values
1 row is stored for this page| Field | Field type | Value |
|---|---|---|
| generic | String | Nifedipine |
| brand | String | Procardia, Procardia XL, Adalat CC, Afeditab CR |
| structure | File | |
| classes | List of String, delimiter: , | [[:Category:Calcium_channel_blockers|Calcium channel blocker (dihydropyridine)]] • [[:Category:Antihypertensives|Antihypertensive]] • [[:Category:Antianginals|Antianginal]] • [[:Category:Tocolytics|Tocolytic (off-label)]] |
| mechanism | String | |
| uses | String | '"`UNIQ--vote-00000747-QINU`"', '"`UNIQ--vote-00000748-QINU`"', '"`UNIQ--vote-00000749-QINU`"', '"`UNIQ--vote-0000074A-QINU`"', '"`UNIQ--vote-0000074B-QINU`"', '"`UNIQ--vote-0000074C-QINU`"' |
| starting_dose | String | ER 30-60 mg PO once daily; immediate-release 10 mg PO TID (now rarely used for hypertension due to reflex tachycardia) |
| preparations | String | 10, 20 mg IR capsules; 30, 60, 90 mg ER tablets |
| fda_max | String | 120 mg/d (ER); IR not for chronic hypertension |
| pill_id | Text | |
| routes | List of String, delimiter: , | Oral; sublingual IR is discouraged (uncontrolled BP drops • MI reports) |
| onset | String | IR 20 minutes; ER ~6 hours |
| duration | String | IR 4-8 hours; ER 24 hours |
| halflife | String | 2-5 hours (IR); ER formulations extend functional duration via osmotic/matrix release'"`UNIQ--ref-0000074D-QINU`"' |
| bioavailability | String | ~50% IR (extensive first-pass via CYP3A4); ER products release-rate-limited'"`UNIQ--ref-0000074E-QINU`"' |
| pregnancy | String | Oral nifedipine is one of the preferred agents for severe hypertension in pregnancy and for tocolysis in preterm labor.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> |
| legal | String | [[USLegal:Prescription only|Rx-only]] in US |