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Page values for "Norethindrone"

From Pharmacopedia
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"Medicines" values

1 row is stored for this page
FieldField typeValue
genericStringNorethindrone (norethisterone outside US)
brandStringAygestin (5 mg, Rx); Camila, Errin, Heather, Jolivette, Nor-QD, Ortho Micronor, Sharobel (0.35 mg POPs); component of many COCs
structureFile
classesList of String, delimiter: ,[[:Category:Progestins|Progestin (synthetic progestogen)]] [[:Category:Hormonal_contraceptives|Hormonal contraceptive]] [[:Category:Sex_hormones|Sex hormone]]
mechanismString'"`UNIQ--vote-000013EE-QINU`"' Higher-dose Aygestin (5 mg) achieves more reliable ovulation suppression and is used for endometriosis and DUB. POP requires strict daily timing because the 24-hour cervical-mucus effect window is narrower than COC'"`UNIQ--ref-000013EF-QINU`"'.
usesString'"`UNIQ--vote-000013F0-QINU`"', '"`UNIQ--vote-000013F1-QINU`"', '"`UNIQ--vote-000013F2-QINU`"', '"`UNIQ--vote-000013F3-QINU`"', '"`UNIQ--vote-000013F4-QINU`"'
starting_doseStringPOP: 0.35 mg PO daily continuously (no placebo week); high-dose 5 mg Aygestin for amenorrhea/endometriosis 5-10 mg/d
preparationsString0.35 mg POP tablets; 5 mg tablets (Aygestin); component of COCs and combination HRT
fda_maxStringIndication-specific
pill_idText
routesList of String, delimiter: ,Oral
onsetStringContraception within 48 hours of starting (POP); endometrial effects days
durationString~24 hours per dose (strict timing required for POP — within 3-hour window each day)
halflifeString~8 hours'"`UNIQ--ref-000013F5-QINU`"'
bioavailabilityString~65% (oral)'"`UNIQ--ref-000013F6-QINU`"'
pregnancyStringContraindicated in known pregnancy (Aygestin); the 0.35 mg POP is not teratogenic and does not need to be discontinued before conception planning.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup>
legalString[[USLegal:Prescription only|Rx-only]] in US (note: norgestrel 0.075 mg POP is now OTC as Opill since 2023, but norethindrone POP remains Rx)