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Page values for "Polyethylene Glycol 3350"

From Pharmacopedia
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"Medicines" values

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FieldField typeValue
genericStringPolyethylene glycol 3350 (PEG 3350)
brandStringMiraLAX (OTC), GlycoLax, GoLYTELY (with electrolytes for bowel prep), CoLyte, MoviPrep, NuLYTELY
structureFile
classesList of String, delimiter: ,[[:Category:Osmotic_laxatives|Osmotic laxative]] [[:Category:Bowel_preparation_agents|Bowel preparation agent]]
mechanismString'"`UNIQ--vote-0000132D-QINU`"' Electrolyte-balanced bowel-prep formulations are designed to be iso-osmotic with plasma so the volume passes through without net fluid or electrolyte shifts, the basis of their safety for whole-bowel evacuation.
usesString'"`UNIQ--vote-0000132E-QINU`"', '"`UNIQ--vote-0000132F-QINU`"', '"`UNIQ--vote-00001330-QINU`"'
starting_doseStringConstipation: 17 g (one capful) PO daily dissolved in 4-8 oz fluid; bowel prep: 4 L of PEG-electrolyte solution split-dose evening before and morning of procedure
preparationsString17 g (OTC) and 14 g (Rx) powder packets; 238, 510, 527 g bottles; PEG-electrolyte preparations 4 L (GoLYTELY, NuLYTELY)
fda_maxStringIndication-specific; bowel prep regimens reach 4 L cumulative
pill_idText
routesList of String, delimiter: ,Oral
onsetStringConstipation: 1-3 days; bowel prep: 1-3 hours after starting
durationStringHours
halflifeStringNot meaningfully described (negligible systemic absorption)
bioavailabilityString<0.1% systemic absorption (PEG 3350 is too large to absorb intact)
pregnancyStringGenerally considered safe due to minimal systemic absorption.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup>
legalStringOTC (MiraLAX) and [[USLegal:Prescription only|Rx-only]] (electrolyte solutions for bowel prep) in US