Page values for "Psilocybin"

Nav

"Medicines" values

1 row is stored for this page

Field	Field type	Value
generic	`String`	Psilocybin
brand	`String`	COMP360 (Compass Pathways, investigational synthesized clinical formulation)
structure	`File`
classes	List of `String`, delimiter: `,`	[[:Category:Psychedelics\|Psychedelic]] • [[:Category:Classical Psychedelics (Serotonergic)\|Serotonergic psychedelic]] • [[:Category:Tryptamines\|Tryptamine]]
mechanism	`String`	Prodrug to [[Psilocin\|psilocin]] (4-hydroxy-N,N-dimethyltryptamine), a partial agonist at the [[Receptor:5-HT2A\|5-HT2A]] serotonin receptor; the action that defines the classical-psychedelic mechanism
uses	`String`	(investigational) '"`UNIQ--vote-000000EF-QINU`"', '"`UNIQ--vote-000000F0-QINU`"', '"`UNIQ--vote-000000F1-QINU`"', '"`UNIQ--vote-000000F2-QINU`"', '"`UNIQ--vote-000000F3-QINU`"'
starting_dose	`String`	Modern clinical-trial standard: 25 mg synthesized psilocybin, single oral dose with psychological support
preparations	`String`	Synthesized psilocybin capsules (COMP360 and other investigational formulations); dried whole [[Psilocybe\|Psilocybe]] mushrooms (variable potency, no legal supply chain in most jurisdictions); psilocybin truffles (Psilocybe sclerotia, legal in the Netherlands)
fda_max	`String`	Not FDA-approved; clinical-trial protocols use up to 30 mg in adult investigational dosing
pill_id	`Text`	Investigational only; not commercially available outside clinical trials and regulated services programs
routes	List of `String`, delimiter: `,`	Oral
onset	`String`	20-45 min subjective onset; psilocin formation from psilocybin requires intestinal and hepatic alkaline phosphatase
duration	`String`	4-6 hours
halflife	`String`	Psilocin: ~2-3 h; psilocybin itself is a prodrug, dephosphorylated within minutes of absorption
bioavailability	`String`	Oral bioavailability of psilocin from administered psilocybin approximately 50%
pregnancy	`String`	Not studied in human pregnancy; no approved clinical use in any population
legal	`String`