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Page values for "Ticagrelor"

From Pharmacopedia
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"Medicines" values

1 row is stored for this page
FieldField typeValue
genericStringTicagrelor
brandStringBrilinta
structureFile
classesList of String, delimiter: ,[[:Category:Antiplatelet_agents|Antiplatelet agent]] [[:Category:P2Y12_inhibitors|P2Y12 receptor inhibitor (reversible)]] [[:Category:Cyclopentyltriazolopyrimidines|Cyclopentyltriazolopyrimidine]]
mechanismString
usesString'"`UNIQ--vote-00000C8F-QINU`"', '"`UNIQ--vote-00000C90-QINU`"', '"`UNIQ--vote-00000C91-QINU`"'
starting_doseStringACS/PCI: 180 mg PO loading dose, then 90 mg PO BID for 12 months; long-term post-MI: 60 mg BID
preparationsString60, 90 mg tablets
fda_maxString90 mg BID (acute year); 60 mg BID (chronic post-MI)
pill_idText
routesList of String, delimiter: ,Oral
onsetStringAntiplatelet effect within 30 minutes of loading dose (faster than clopidogrel)
durationString12 hours
halflifeString~7 hours (parent); ~9 hours (active AR-C124910XX metabolite, accounts for ~30-40% of activity)'"`UNIQ--ref-00000C92-QINU`"'
bioavailabilityString~36% (oral)'"`UNIQ--ref-00000C93-QINU`"'
pregnancyStringLimited data; weigh against alternatives.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup>
legalString[[USLegal:Prescription only|Rx-only]] in US. Carries a '''Boxed Warning''' for bleeding risk and against aspirin maintenance doses above 100 mg/d (reduces ticagrelor efficacy, per PLATO subgroup analysis)'"`UNIQ--ref-00000C94-QINU`"'