Toggle menu
Toggle preferences menu
Toggle personal menu
Not logged in
Your IP address will be publicly visible if you make any edits.

Page values for "Amlodipine"

From Pharmacopedia
More actions

"Medicines" values

1 row is stored for this page
FieldField typeValue
genericStringAmlodipine
brandStringNorvasc, Katerzia
structureFile
classesList of String, delimiter: ,[[:Category:Calcium_channel_blockers|Calcium channel blocker]] [[:Category:Antihypertensives|Antihypertensive]] [[:Category:Antianginals|Antianginal]]
mechanismString'"`UNIQ--vote-00000073-QINU`"' The long half-life gives smooth, once-daily BP control with low rebound. CYP3A4 substrate; pedal edema is the characteristic, dose-related, non-fluid-overload side effect'"`UNIQ--ref-00000074-QINU`"'.
usesString'"`UNIQ--vote-00000075-QINU`"', '"`UNIQ--vote-00000076-QINU`"', '"`UNIQ--vote-00000077-QINU`"'
starting_doseString2.5-5 mg PO once daily; titrate to 10 mg/d
preparationsString2.5, 5, 10 mg tablets; 1 mg/mL oral suspension
fda_maxString10 mg/d
pill_idText
routesList of String, delimiter: ,Oral
onsetStringBP effect within 24 hours; full effect at 1-2 weeks (long half-life)
durationString24 hours
halflifeString30-50 hours'"`UNIQ--ref-00000078-QINU`"'
bioavailabilityString64-90% (oral; not affected by food)'"`UNIQ--ref-00000079-QINU`"'
pregnancyStringLimited data; case series and registries suggest no major teratogenicity but other antihypertensives (labetalol, nifedipine) are typically preferred.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup>
legalString[[USLegal:Prescription only|Rx-only]] in US