1 row is stored for this page
| Field | Field type | Value |
|---|
| generic | String | Aspirin (acetylsalicylic acid; ASA) |
| brand | String | Bayer, Ecotrin, Bufferin, St. Joseph (low-dose 81 mg), Excedrin (with acetaminophen and caffeine) |
| structure | File | |
| classes | List of String, delimiter: , | [[:Category:NSAIDs|Non-steroidal anti-inflammatory (NSAID)]] • [[:Category:Antiplatelets|Antiplatelet]] • [[:Category:Analgesics|Analgesic]] • [[:Category:Antipyretics|Antipyretic]] |
| mechanism | String | |
| uses | String | '"`UNIQ--vote-0000001F-QINU`"', '"`UNIQ--vote-00000020-QINU`"', '"`UNIQ--vote-00000021-QINU`"', '"`UNIQ--vote-00000022-QINU`"', '"`UNIQ--vote-00000023-QINU`"', '"`UNIQ--vote-00000024-QINU`"', '"`UNIQ--vote-00000025-QINU`"', '"`UNIQ--vote-00000026-QINU`"' |
| starting_dose | String | Antiplatelet: 81 mg PO once daily. Acute MI/stroke: 162-325 mg chewed. Analgesic: 325-650 mg PO every 4-6 hours as needed |
| preparations | String | Tablets 81 (low-dose), 325, 500, 650 mg; chewable 81 mg; enteric-coated tablets; effervescent tablets; suppositories |
| fda_max | String | 4000 mg/day (analgesic) |
| pill_id | Text | |
| routes | List of String, delimiter: , | Oral • rectal |
| onset | String | Antiplatelet effect within 30-60 minutes; analgesic effect 30-60 minutes |
| duration | String | '''Antiplatelet effect lasts the platelet's lifetime (~7-10 days)''' due to irreversible COX-1 acetylation; analgesic 4-6 hours |
| halflife | String | Aspirin 15-30 minutes; salicylate metabolite 2-3 hours (concentration-dependent, saturable at high doses)'"`UNIQ--ref-00000027-QINU`"' |
| bioavailability | String | ~50% (oral; reduced by buffering and enteric coating but onset clinically similar)'"`UNIQ--ref-00000028-QINU`"' |
| pregnancy | String | Low-dose (81 mg) safe and indicated for preeclampsia prophylaxis after 12 weeks in high-risk patients per USPSTF; high-dose aspirin avoid third trimester due to premature ductus arteriosus closure and bleeding risk |
| legal | String | [[USLegal:Over-the-counter|OTC]] in US at all standard strengths |
