1 row is stored for this page
| Field | Field type | Value |
|---|
| generic | String | Carbamazepine |
| brand | String | Tegretol (IR, XR, suspension), Carbatrol (ER), Equetro (ER for bipolar), Epitol |
| structure | File | |
| classes | List of String, delimiter: , | [[:Category:Anticonvulsants|Anticonvulsant]] • [[:Category:Mood stabilizers|Mood stabilizer]] • [[:Category:Sodium channel blockers|Sodium channel blocker]] |
| mechanism | String | |
| uses | String | '"`UNIQ--vote-00000019-QINU`"', '"`UNIQ--vote-0000001A-QINU`"', '"`UNIQ--vote-0000001B-QINU`"', '"`UNIQ--vote-0000001C-QINU`"' |
| starting_dose | String | Seizures: 200 mg PO BID, titrate by 200 mg/week to 800-1200 mg/day. Trigeminal neuralgia: 100-200 mg BID, titrate to 200-400 mg TID. Bipolar: 200 mg BID, titrate to 1600 mg/day |
| preparations | String | IR tablets 200 mg; chewable 100 mg; oral suspension 100 mg/5 mL; XR tablets 100, 200, 400 mg (Tegretol XR); ER capsules 100, 200, 300 mg (Carbatrol, Equetro) |
| fda_max | String | 1200 mg/day (adult seizures); 1600 mg/day (bipolar mania) |
| pill_id | Text | |
| routes | List of String, delimiter: , | Oral |
| onset | String | Anticonvulsant effect within days; trigeminal neuralgia relief 24-72 hours; mood-stabilizing effect over weeks |
| duration | String | BID-QID dosing (IR); BID for ER formulations |
| halflife | String | '''Autoinduction''': 25-65 hours initially, falling to 12-17 hours after 2-3 weeks of dosing as carbamazepine induces its own CYP3A4 metabolism. Major clinical implication: doses require re-titration after the autoinduction period'"`UNIQ--ref-0000001D-QINU`"' |
| bioavailability | String | ~80% (oral)'"`UNIQ--ref-0000001E-QINU`"' |
| pregnancy | String | '''Substantial teratogenic risk''' including neural tube defects, craniofacial malformations, cardiac defects, and growth restriction; folic acid supplementation and effective contraception are required in reproductive-age patients'"`UNIQ--ref-0000001F-QINU`"' |
| legal | String | [[USLegal:Prescription only|Rx-only]] in US |
