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Page values for "Donepezil"

From Pharmacopedia
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"Medicines" values

1 row is stored for this page
FieldField typeValue
genericStringDonepezil
brandStringAricept (oral), Adlarity (transdermal patch)
structureFile
classesList of String, delimiter: ,[[:Category:Anti-dementia medicines|Anti-dementia medicine]] [[:Category:Acetylcholinesterase inhibitors|Acetylcholinesterase inhibitor]]
mechanismString
usesString'"`UNIQ--vote-00000017-QINU`"', '"`UNIQ--vote-00000018-QINU`"', '"`UNIQ--vote-00000019-QINU`"', '"`UNIQ--vote-0000001A-QINU`"'
starting_doseString5 mg PO once daily at bedtime; titrate to 10 mg/day after 4-6 weeks. Severe Alzheimer disease: may escalate to 23 mg/day. Adlarity patch: 5 or 10 mg/day applied weekly
preparationsStringOral tablets 5, 10, 23 mg; ODT 5, 10 mg; Adlarity transdermal patch 5, 10 mg/day (weekly application)
fda_maxString23 mg/day
pill_idText
routesList of String, delimiter: ,Oral transdermal
onsetStringCognitive effect emerges gradually over weeks to months; ceiling effect at the therapeutic dose
durationString24 hours (once-daily dosing)
halflifeString~70 hours (long, supports once-daily dosing without peak-trough variation)'"`UNIQ--ref-0000001B-QINU`"'
bioavailabilityString~100% (oral)'"`UNIQ--ref-0000001C-QINU`"'
pregnancyStringLimited human data; rarely indicated in pregnancy given the patient population.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup>
legalString[[USLegal:Prescription only|Rx-only]] in US