1 row is stored for this page
| Field | Field type | Value |
|---|
| generic | String | Epinephrine (adrenaline) |
| brand | String | EpiPen, EpiPen Jr, Auvi-Q, Adrenaclick, Symjepi; many generic |
| structure | File | |
| classes | List of String, delimiter: , | [[:Category:Catecholamines|Catecholamine]] • [[:Category:Sympathomimetics|Sympathomimetic]] • [[:Category:Vasopressors|Vasopressor]] • [[:Category:Inotropes|Inotrope]] |
| mechanism | String | '"`UNIQ--vote-00000E4A-QINU`"' The narrow safe-bolus window for IV use (sharp risk of arrhythmia, hypertensive emergency, intracerebral hemorrhage) is why anaphylaxis dosing is '''IM, not IV''', outside critical care'"`UNIQ--ref-00000E4B-QINU`"'. |
| uses | String | '"`UNIQ--vote-00000E4C-QINU`"', '"`UNIQ--vote-00000E4D-QINU`"', '"`UNIQ--vote-00000E4E-QINU`"', '"`UNIQ--vote-00000E4F-QINU`"', '"`UNIQ--vote-00000E50-QINU`"', '"`UNIQ--vote-00000E51-QINU`"' |
| starting_dose | String | Anaphylaxis IM 0.3-0.5 mg (adult) into lateral thigh, repeat q5-15 minutes prn; pediatric 0.01 mg/kg IM (max 0.3 mg, max 0.5 mg in adolescents); cardiac arrest 1 mg IV/IO q3-5 minutes; severe asthma neb 0.1 mg/kg up to 5 mg; never IV bolus for anaphylaxis outside critical care |
| preparations | String | Auto-injectors 0.15 mg (Jr/pediatric), 0.3 mg (adult); 1 mg/mL (1:1,000) ampules for IM/SC use; 0.1 mg/mL (1:10,000) for IV use; 2.25% racemic nebulizer |
| fda_max | String | Indication-specific; ACLS no fixed cumulative ceiling |
| pill_id | Text | |
| routes | List of String, delimiter: , | IM • IV • SC (less common) • nebulized • intracardiac (historical only) • endotracheal (legacy ACLS • not preferred) |
| onset | String | IM: 5-10 minutes; IV: seconds; nebulized: 5-10 minutes |
| duration | String | 5-15 minutes |
| halflife | String | ~2 minutes'"`UNIQ--ref-00000E52-QINU`"' |
| bioavailability | String | IM/SC ~100%; oral negligible (extensive first-pass and gut metabolism — hence the no-oral route)'"`UNIQ--ref-00000E53-QINU`"' |
| pregnancy | String | Used in life-threatening obstetric anaphylaxis without hesitation; benefits clearly outweigh.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> |
| legal | String | [[USLegal:Prescription only|Rx-only]] in US |
