1 row is stored for this page
| Field | Field type | Value |
|---|
| generic | String | Exenatide |
| brand | String | Byetta (twice-daily), Bydureon BCise (weekly) |
| structure | File | |
| classes | List of String, delimiter: , | [[GLP-1 receptor agonist]] · [[Antidiabetic medicines|Antidiabetic]] · First-in-class incretin mimetic |
| mechanism | String | Agonist of the [[GLP-1 receptor]]; exendin-4 derivative from Gila monster venom. |
| uses | String | [[Type 2 diabetes mellitus]] (adjunct, second-line) |
| starting_dose | String | Byetta: 5 µg SC twice daily, within 60 min before morning and evening meals'"`UNIQ--ref-000000E3-QINU`"' · Bydureon BCise: 2 mg SC once weekly'"`UNIQ--ref-000000E4-QINU`"' |
| preparations | String | Byetta pre-filled multi-dose pen: 5 µg / 10 µg per dose'"`UNIQ--ref-000000E5-QINU`"' · Bydureon BCise single-dose autoinjector: 2 mg extended-release microsphere suspension'"`UNIQ--ref-000000E6-QINU`"' |
| fda_max | String | 10 µg twice daily (Byetta)'"`UNIQ--ref-000000E7-QINU`"' · 2 mg once weekly (Bydureon BCise)'"`UNIQ--ref-000000E8-QINU`"' |
| pill_id | Text | |
| routes | List of String, delimiter: , | Subcutaneous (abdomen • thigh • upper arm)'"`UNIQ--ref-000000E9-QINU`"' |
| onset | String | Glycemic effect within hours (Byetta); weeks (Bydureon, extended-release microsphere)'"`UNIQ--ref-000000EA-QINU`"' |
| duration | String | ~10 hours (Byetta)'"`UNIQ--ref-000000EB-QINU`"' · ~7 days steady-state (Bydureon, after ~6–7 weeks of weekly dosing to reach steady state)'"`UNIQ--ref-000000EC-QINU`"' |
| halflife | String | ~2.4 hours (Byetta, short, hence the BID schedule)'"`UNIQ--ref-000000ED-QINU`"' · Effective release half-life ~2 weeks (Bydureon)'"`UNIQ--ref-000000EE-QINU`"' |
| bioavailability | String | SC ~65%–75%<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> |
| pregnancy | String | Avoid. Discontinue before planned pregnancy.'"`UNIQ--ref-000000EF-QINU`"' |
| legal | String | Rx-only;'"`UNIQ--ref-000000F0-QINU`"' not a controlled substance |
