Page values for "Irbesartan"
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"Medicines" values
1 row is stored for this page| Field | Field type | Value |
|---|---|---|
| generic | String | Irbesartan |
| brand | String | Avapro |
| structure | File | |
| classes | List of String, delimiter: , | [[:Category:Angiotensin_receptor_blockers|Angiotensin receptor blocker (ARB)]] • [[:Category:Antihypertensives|Antihypertensive]] |
| mechanism | String | '"`UNIQ--vote-0000083E-QINU`"' CYP2C9 substrate; no clinically active metabolites. The IDNT trial established renoprotection in diabetic nephropathy independent of BP lowering, contributing to the ARB class indication in T2DM with proteinuria'"`UNIQ--ref-0000083F-QINU`"'. |
| uses | String | '"`UNIQ--vote-00000840-QINU`"', '"`UNIQ--vote-00000841-QINU`"' |
| starting_dose | String | 150 mg PO once daily; titrate to 300 mg if needed |
| preparations | String | 75, 150, 300 mg tablets |
| fda_max | String | 300 mg/d |
| pill_id | Text | |
| routes | List of String, delimiter: , | Oral |
| onset | String | BP effect within 1-2 weeks |
| duration | String | 24 hours |
| halflife | String | 11-15 hours'"`UNIQ--ref-00000842-QINU`"' |
| bioavailability | String | 60-80% (oral; not significantly affected by food)'"`UNIQ--ref-00000843-QINU`"' |
| pregnancy | String | '''Contraindicated in pregnancy''' (all trimesters); fetal renal injury, oligohydramnios, hypocalvaria, hypotension. Stop on detection'"`UNIQ--ref-00000844-QINU`"' |
| legal | String | [[USLegal:Prescription only|Rx-only]] in US |