Page values for "Ketoconazole"
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"Medicines" values
1 row is stored for this page| Field | Field type | Value |
|---|---|---|
| generic | String | Ketoconazole |
| brand | String | Nizoral (oral discontinued in US for most fungal indications; topical still widely available) |
| structure | File | |
| classes | List of String, delimiter: , | [[:Category:Antifungals|Antifungal (imidazole)]] • [[:Category:Topical_antifungals|Topical antifungal]] |
| mechanism | String | |
| uses | String | '"`UNIQ--vote-00000884-QINU`"', '"`UNIQ--vote-00000885-QINU`"', '"`UNIQ--vote-00000886-QINU`"', '"`UNIQ--vote-00000887-QINU`"' |
| starting_dose | String | Topical 2% shampoo twice weekly for seborrheic dermatitis or tinea versicolor; oral use restricted by 2013 FDA action to indications where alternatives have failed |
| preparations | String | 1% (OTC), 2% (Rx) shampoo; 2% cream; 2% gel; 200 mg oral tablet (rarely used now) |
| fda_max | String | Topical: regimen-specific; oral: 400 mg/d in remaining specialty indications |
| pill_id | Text | |
| routes | List of String, delimiter: , | Topical (cream • shampoo • gel); oral (restricted) |
| onset | String | Topical hours; oral days |
| duration | String | Hours per application (topical); 24 hours (oral) |
| halflife | String | Topical: not meaningfully described; oral 2-8 hours'"`UNIQ--ref-00000888-QINU`"' |
| bioavailability | String | Topical: minimal systemic; oral: pH-dependent, requires gastric acid'"`UNIQ--ref-00000889-QINU`"' |
| pregnancy | String | Topical generally safe; oral avoided.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> |
| legal | String | OTC (1% shampoo) and [[USLegal:Prescription only|Rx-only]] (higher strengths, oral) in US. Oral form carries a '''Boxed Warning''' for hepatotoxicity and is restricted by FDA to refractory fungal infections where no alternatives are available |