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Page values for "Lactulose"

From Pharmacopedia
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"Medicines" values

1 row is stored for this page
FieldField typeValue
genericStringLactulose
brandStringKristalose, Constulose, Generlac, Enulose
structureFile
classesList of String, delimiter: ,[[:Category:Osmotic_laxatives|Osmotic laxative]] [[:Category:Disaccharides|Non-absorbable disaccharide]] [[:Category:Hepatic_encephalopathy_treatments|Hepatic encephalopathy treatment]]
mechanismString
usesString'"`UNIQ--vote-00000F5C-QINU`"', '"`UNIQ--vote-00000F5D-QINU`"'
starting_doseStringConstipation: 15-30 mL PO daily (titrate to 1-2 soft stools/day); hepatic encephalopathy: 20-30 g (30-45 mL) PO/PR every 1-2 hours acutely until soft stools, then BID-QID to target 2-3 soft stools/day
preparationsString10 g/15 mL solution (Constulose); 10 g, 20 g powder packets (Kristalose)
fda_maxStringIndication-specific; HE may require high-volume dosing
pill_idText
routesList of String, delimiter: ,Oral rectal (enema especially in acute HE)
onsetStringConstipation: 24-48 hours; HE: ammonia reduction within hours of stool production
durationStringHours
halflifeStringNot meaningfully described — lactulose is not significantly absorbed
bioavailabilityString<3% systemic absorption (the basis of the safety and mechanism)'"`UNIQ--ref-00000F5E-QINU`"'
pregnancyStringGenerally considered safe (minimal systemic absorption).<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup>
legalString[[USLegal:Prescription only|Rx-only]] in US