1 row is stored for this page
| Field | Field type | Value |
|---|
| generic | String | Lidocaine (hydrochloride) |
| brand | String | Xylocaine (injectable, oral solution, topical), Lidoderm (patch), ZTLido (patch), Glydo (jelly), EMLA (with prilocaine, topical) |
| structure | File | |
| classes | List of String, delimiter: , | [[:Category:Local anesthetics|Local anesthetic (amide class)]] • [[:Category:Anesthetics|Anesthetic]] • [[:Category:Antiarrhythmics|Antiarrhythmic (Vaughan Williams Class IB)]] |
| mechanism | String | |
| uses | String | '"`UNIQ--vote-0000001B-QINU`"', '"`UNIQ--vote-0000001C-QINU`"', '"`UNIQ--vote-0000001D-QINU`"', '"`UNIQ--vote-0000001E-QINU`"', '"`UNIQ--vote-0000001F-QINU`"' |
| starting_dose | String | Infiltration: 1-2% solution; '''4.5 mg/kg ceiling without epinephrine, 7 mg/kg with epinephrine'''. IV antiarrhythmic: 1-1.5 mg/kg bolus then infusion 1-4 mg/minute. Lidoderm patch: up to 3 patches per 12 hours |
| preparations | String | Injection 0.5-4% solutions (with and without epinephrine); topical cream 4-5%; transdermal patch 5% (Lidoderm), 1.8% (ZTLido); oral 2% viscous solution; jelly 2%; ophthalmic |
| fda_max | String | '''4.5 mg/kg (without epinephrine), 7 mg/kg (with epinephrine)''' for infiltration; serum level monitoring required for prolonged IV antiarrhythmic use |
| pill_id | Text | |
| routes | List of String, delimiter: , | Topical • infiltration • intravenous • regional anesthesia (spinal • epidural • nerve block) • oral mucosal |
| onset | String | <1 minute (IV); 1-2 minutes (infiltration); 30+ minutes (patch on adult skin, faster on thinner pediatric skin) |
| duration | String | 30-90 minutes (infiltration without epinephrine); 90-200 minutes (with epinephrine); 12 hours (patch) |
| halflife | String | 1.5-2 hours'"`UNIQ--ref-00000020-QINU`"' |
| bioavailability | String | ~35% (oral, extensive first-pass; not used orally for systemic effect); ~100% (IV)'"`UNIQ--ref-00000021-QINU`"' |
| pregnancy | String | Extensive use experience in obstetric anesthesia; broadly considered safe'"`UNIQ--ref-00000022-QINU`"' |
| legal | String | [[USLegal:Prescription only|Rx-only]] for most formulations; some low-concentration topical formulations are [[USLegal:Over-the-counter|OTC]] (4% cream) |
