1 row is stored for this page
| Field | Field type | Value |
|---|
| generic | String | Lisdexamfetamine (dimesylate) |
| brand | String | Vyvanse, Elvanse (EU) |
| structure | File | |
| classes | List of String, delimiter: , | [[:Category:Psychostimulants|Psychostimulant]] • [[:Category:Amphetamines|Amphetamine]] • [[:Category:ADHD medicines|ADHD medicine]] • [[:Category:Schedule II controlled substances|Schedule II controlled substance]] |
| mechanism | String | '"`UNIQ--vote-00000013-QINU`"' Once converted, dextroamphetamine acts by displacing dopamine and norepinephrine from presynaptic vesicles via VMAT-2 and reversing DAT and NET transport, the shared mechanism of all amphetamine-class agents'"`UNIQ--ref-00000014-QINU`"'. |
| uses | String | '"`UNIQ--vote-00000015-QINU`"', '"`UNIQ--vote-00000016-QINU`"' |
| starting_dose | String | ADHD: 30 mg PO once daily in the morning; titrate by 10-20 mg weekly to clinical effect. Binge-eating disorder: 30 mg/day, titrate to 50-70 mg/day |
| preparations | String | Capsules 10, 20, 30, 40, 50, 60, 70 mg; chewable tablets 10, 20, 30, 40, 50, 60 mg |
| fda_max | String | 70 mg/day |
| pill_id | Text | |
| routes | List of String, delimiter: , | Oral |
| onset | String | 1-2 hours (slower than immediate-release amphetamine because activation requires enzymatic cleavage in red blood cells) |
| duration | String | 10-12 hours (smoother profile than immediate-release amphetamine salts) |
| halflife | String | Parent lisdexamfetamine <1 hour; dextroamphetamine 10-12 hours after release'"`UNIQ--ref-00000017-QINU`"' |
| bioavailability | String | ~96% after red blood cell hydrolytic cleavage releases dextroamphetamine'"`UNIQ--ref-00000018-QINU`"' |
| pregnancy | String | Limited human data; the amphetamine class is associated with intrauterine growth restriction and neonatal withdrawal symptoms.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> |
| legal | String | [[USLegal:Schedule II|Schedule II controlled substance]] in US'"`UNIQ--ref-00000019-QINU`"' |
