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Page values for "Loratadine"

From Pharmacopedia
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"Medicines" values

1 row is stored for this page
FieldField typeValue
genericStringLoratadine
brandStringClaritin, Alavert, Tavist ND
structureFile
classesList of String, delimiter: ,[[:Category:H1_receptor_antagonists|Histamine H1 receptor antagonist (second-generation)]] [[:Category:Antihistamines|Antihistamine]]
mechanismString'"`UNIQ--vote-0000061E-QINU`"' Less reliably anticholinergic than first-generation H1s; minimal antiemetic effect. Desloratadine (Clarinex) is the active enantiomer-of-metabolite version marketed as a Rx alternative.
usesString'"`UNIQ--vote-0000061F-QINU`"', '"`UNIQ--vote-00000620-QINU`"'
starting_doseString10 mg PO once daily
preparationsString10 mg tablets; 5 mg ODT and chewables; 1 mg/mL oral syrup; combo Claritin-D (with pseudoephedrine, behind-counter)
fda_maxString10 mg/d (adults)
pill_idText
routesList of String, delimiter: ,Oral
onsetString1-3 hours (slower onset than cetirizine; symptom relief somewhat less)
durationString24 hours
halflifeString~8 hours (parent); ~28 hours (desloratadine, the active metabolite, marketed separately as Clarinex)'"`UNIQ--ref-00000621-QINU`"'
bioavailabilityStringHigh (oral; food prolongs absorption modestly)'"`UNIQ--ref-00000622-QINU`"'
pregnancyStringGenerally considered safe; widely used. Loratadine and cetirizine are the most-recommended 2nd-gen H1s in pregnancy and lactation.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup>
legalStringOTC in US