1 row is stored for this page
| Field | Field type | Value |
|---|
| generic | String | Lovastatin |
| brand | String | Altoprev (ER), Mevacor (discontinued US); mostly generic |
| structure | File | |
| classes | List of String, delimiter: , | [[:Category:Statins|Statin]] • [[:Category:Lipid-lowering_agents|Lipid-lowering agent]] |
| mechanism | String | |
| uses | String | '"`UNIQ--vote-00000805-QINU`"', '"`UNIQ--vote-00000806-QINU`"' |
| starting_dose | String | 20 mg PO once daily with the evening meal; titrate to 40-80 mg/d |
| preparations | String | 10, 20, 40 mg tablets; 20, 40, 60 mg ER tablets |
| fda_max | String | 80 mg/d (40 mg/d if combined with diltiazem, verapamil, danazol; lower limits with various interactions) |
| pill_id | Text | |
| routes | List of String, delimiter: , | Oral |
| onset | String | LDL lowering at 2 weeks, max by 4 weeks |
| duration | String | 24 hours |
| halflife | String | ~2-4 hours (parent and active β-hydroxy acid metabolite); pharmacodynamic effect 24 hours via target turnover'"`UNIQ--ref-00000807-QINU`"' |
| bioavailability | String | <5% (extensive hepatic first-pass; food enhances absorption of IR, hence the evening-meal dosing)'"`UNIQ--ref-00000808-QINU`"' |
| pregnancy | String | Previously Category X; FDA removed the blanket statin contraindication in pregnancy in 2021.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> |
| legal | String | [[USLegal:Prescription only|Rx-only]] in US |
