Toggle menu
Toggle preferences menu
Toggle personal menu
Not logged in
Your IP address will be publicly visible if you make any edits.

Page values for "Methadone"

From Pharmacopedia
More actions

"Medicines" values

1 row is stored for this page
FieldField typeValue
genericStringMethadone
brandStringDolophine, Methadose, Diskets (oral dispersible tablets for OTPs)
structureFile
classesList of String, delimiter: ,[[:Category:Opioid analgesics|Opioid analgesic (full mu-agonist)]] [[:Category:NMDA antagonists|NMDA receptor antagonist]] [[:Category:Schedule II controlled substances|Schedule II controlled substance]]
mechanismString
usesString'"`UNIQ--vote-0000004C-QINU`"', '"`UNIQ--vote-0000004D-QINU`"', '"`UNIQ--vote-0000004E-QINU`"'
starting_doseString
preparationsStringTablets 5, 10, 40 mg (40 mg dispersible restricted to OTPs); oral concentrate 10 mg/mL; oral solution 1, 2, 10 mg/mL; injection 10 mg/mL
fda_maxStringNo formal hard ceiling; in MOUD maintenance, doses typically remain at or below 120 mg/day with higher doses reserved for documented under-treatment after careful clinical assessment
pill_idText
routesList of String, delimiter: ,Oral (primary) IV IM SC sublingual; rectal off-label
onsetStringOral analgesic effect 30-60 minutes; opioid-withdrawal suppression 30 minutes (oral); IV ~10 minutes
durationStringAnalgesic effect 4-8 hours (much shorter than half-life would suggest, due to receptor kinetics); MOUD effect (opioid withdrawal suppression) 24-36 hours per single daily dose
halflifeString
bioavailabilityString~70-85% (oral, high relative to other opioids)
pregnancyString
legalString