Page values for "Methimazole"
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"Medicines" values
1 row is stored for this page| Field | Field type | Value |
|---|---|---|
| generic | String | Methimazole (thiamazole) |
| brand | String | Tapazole; outside US Mercazole |
| structure | File | |
| classes | List of String, delimiter: , | [[:Category:Antithyroid_agents|Antithyroid agent]] • [[:Category:Thionamides|Thionamide]] |
| mechanism | String | '"`UNIQ--vote-00000ECD-QINU`"' Agranulocytosis is the most-feared adverse effect (~0.3%, usually first 90 days of treatment; warn patients to seek urgent CBC for fever or severe sore throat). Hepatotoxicity is class-recognized but more often associated with PTU'"`UNIQ--ref-00000ECE-QINU`"'. |
| uses | String | '"`UNIQ--vote-00000ECF-QINU`"', '"`UNIQ--vote-00000ED0-QINU`"', '"`UNIQ--vote-00000ED1-QINU`"', '"`UNIQ--vote-00000ED2-QINU`"' |
| starting_dose | String | 10-40 mg PO daily depending on hyperthyroidism severity; titrate by clinical and biochemical response (target TSH/free T4) |
| preparations | String | 5, 10 mg tablets |
| fda_max | String | 60 mg/d typical |
| pill_id | Text | |
| routes | List of String, delimiter: , | Oral |
| onset | String | Biochemical improvement within 2-4 weeks; full euthyroid state 6-12 weeks |
| duration | String | 24 hours |
| halflife | String | ~4-6 hours (plasma); intrathyroidal accumulation gives a much longer functional duration'"`UNIQ--ref-00000ED3-QINU`"' |
| bioavailability | String | ~93% (oral)'"`UNIQ--ref-00000ED4-QINU`"' |
| pregnancy | String | |
| legal | String | [[USLegal:Prescription only|Rx-only]] in US |