Page values for "Omeprazole"
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"Medicines" values
1 row is stored for this page| Field | Field type | Value |
|---|---|---|
| generic | String | Omeprazole |
| brand | String | Prilosec, Losec, Zegerid |
| structure | File | |
| classes | List of String, delimiter: , | [[:Category:Proton_pump_inhibitors|Proton pump inhibitor (PPI)]] • [[:Category:Antisecretory_agents|Gastric acid suppressant]] |
| mechanism | String | '"`UNIQ--vote-000000D8-QINU`"' Recovery of acid output requires synthesis of new pump enzyme. CYP2C19 substrate; PGx genotype substantially affects exposure and efficacy'"`UNIQ--ref-000000D9-QINU`"'. |
| uses | String | '"`UNIQ--vote-000000DA-QINU`"', '"`UNIQ--vote-000000DB-QINU`"', '"`UNIQ--vote-000000DC-QINU`"', '"`UNIQ--vote-000000DD-QINU`"' |
| starting_dose | String | 20 mg PO once daily 30-60 minutes before breakfast |
| preparations | String | 10, 20, 40 mg delayed-release capsules and tablets; 2 mg/mL oral suspension; immediate-release combo with sodium bicarbonate (Zegerid) |
| fda_max | String | 40 mg/d typical; up to 360 mg/d for Zollinger-Ellison |
| pill_id | Text | |
| routes | List of String, delimiter: , | Oral • IV |
| onset | String | Symptom relief 1-4 days; full acid suppression after 3-5 days of dosing |
| duration | String | 24-72 hours per dose (irreversible enzyme binding; effect outlasts plasma exposure) |
| halflife | String | 0.5-1.5 hours (plasma); pharmacodynamic effect persists 24+ hours'"`UNIQ--ref-000000DE-QINU`"' |
| bioavailability | String | 30-40% (oral; increases with repeated dosing as gastric pH rises)'"`UNIQ--ref-000000DF-QINU`"' |
| pregnancy | String | Widely used in pregnancy; meta-analyses do not show increased malformation risk.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> |
| legal | String | OTC (20 mg) and [[USLegal:Prescription only|Rx-only]] (higher doses) in US |