Page values for "Pharmacopedia:Pharmacogenomics sandbox/Codeine"
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"Medicines" values
1 row is stored for this page| Field | Field type | Value |
|---|---|---|
| generic | String | Codeine |
| brand | String | (multiple, generic dominant) |
| structure | File | |
| classes | List of String, delimiter: , | Opioid • Analgesic • Prodrug |
| mechanism | String | Prodrug; converted to [[Morphine|morphine]] by [[Enzyme:CYP2D6|CYP2D6]] for analgesic action. |
| uses | String | Mild to moderate pain; cough suppression (low-dose). |
| starting_dose | String | Adult: 15–60 mg every 4 hours as needed. |
| preparations | String | Tablet (15, 30, 60 mg); oral solution; combination products (with [[Acetaminophen|acetaminophen]] or ibuprofen). |
| fda_max | String | 360 mg/day |
| pill_id | Text | |
| routes | List of String, delimiter: , | PO (only formulation marketed in the US). |
| onset | String | 30–60 min (PO) |
| duration | String | 4–6 hours |
| halflife | String | 2.5–3 hours |
| bioavailability | String | ~50% (variable, CYP2D6-dependent for analgesic effect). |
| pregnancy | String | Avoid; risk of neonatal opioid withdrawal with chronic use; UM-mother breastfeeding contraindicated. |
| legal | String | US Schedule II (single-entity); Schedule III–V (combination products by content). |
