Page values for "Rosuvastatin"
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"Medicines" values
1 row is stored for this page| Field | Field type | Value |
|---|---|---|
| generic | String | Rosuvastatin |
| brand | String | Crestor, Ezallor |
| structure | File | |
| classes | List of String, delimiter: , | [[:Category:Statins|Statin]] • [[:Category:Lipid-lowering_agents|Lipid-lowering agent]] |
| mechanism | String | '"`UNIQ--vote-000000F7-QINU`"' Minimal CYP3A4 dependence (CYP2C9 minor) reduces drug-drug interactions; transport in and out of hepatocytes is largely via OATP1B1, making SLCO1B1 PGx genotype the most clinically actionable marker for statin-associated myopathy'"`UNIQ--ref-000000F8-QINU`"'. |
| uses | String | '"`UNIQ--vote-000000F9-QINU`"', '"`UNIQ--vote-000000FA-QINU`"', '"`UNIQ--vote-000000FB-QINU`"' |
| starting_dose | String | 10-20 mg PO once daily (5 mg in Asian ancestry, elderly, hypothyroidism, or strong CYP/SLCO1B1 interactions) |
| preparations | String | 5, 10, 20, 40 mg tablets |
| fda_max | String | 40 mg/d (rarely needed; 40 mg restricted to patients not at goal on 20 mg) |
| pill_id | Text | |
| routes | List of String, delimiter: , | Oral |
| onset | String | LDL lowering at 1 week, max by 4 weeks |
| duration | String | 24 hours |
| halflife | String | ~19 hours'"`UNIQ--ref-000000FC-QINU`"' |
| bioavailability | String | ~20% (oral; hydrophilic, minimal CYP metabolism, mostly excreted unchanged in bile)'"`UNIQ--ref-000000FD-QINU`"' |
| pregnancy | String | Previously Category X; FDA removed the blanket statin contraindication in pregnancy in 2021. Use individualized.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> |
| legal | String | [[USLegal:Prescription only|Rx-only]] in US |