Page values for "Sitagliptin"
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"Medicines" values
1 row is stored for this page| Field | Field type | Value |
|---|---|---|
| generic | String | Sitagliptin |
| brand | String | Januvia; with metformin Janumet/Janumet XR |
| structure | File | |
| classes | List of String, delimiter: , | [[:Category:DPP-4_inhibitors|DPP-4 inhibitor]] • [[:Category:Antihyperglycemic_agents|Antihyperglycemic agent]] • [[:Category:Incretin_modulators|Incretin pathway modulator]] |
| mechanism | String | '"`UNIQ--vote-00000762-QINU`"' Largely renally cleared, hence the eGFR-tiered dosing. Rare but well-documented signals: acute pancreatitis (uncertain causal contribution), severe joint pain, and bullous pemphigoid (class effect, especially in older Asian patients)'"`UNIQ--ref-00000763-QINU`"'. |
| uses | String | '"`UNIQ--vote-00000764-QINU`"' |
| starting_dose | String | 100 mg PO once daily (50 mg if CrCl 30-44; 25 mg if <30 or dialysis) |
| preparations | String | 25, 50, 100 mg tablets; combination tablets with metformin |
| fda_max | String | 100 mg/d |
| pill_id | Text | |
| routes | List of String, delimiter: , | Oral |
| onset | String | Postprandial glucose effect within days; HbA1c by 12 weeks |
| duration | String | 24 hours |
| halflife | String | ~12.4 hours'"`UNIQ--ref-00000765-QINU`"' |
| bioavailability | String | ~87% (oral)'"`UNIQ--ref-00000766-QINU`"' |
| pregnancy | String | Limited data; switch to insulin where feasible.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> |
| legal | String | [[USLegal:Prescription only|Rx-only]] in US |