Page values for "Sodium Oxybate"
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"Medicines" values
1 row is stored for this page| Field | Field type | Value |
|---|---|---|
| generic | String | Sodium Oxybate |
| brand | String | Xyrem; Xywav (lower-sodium formulation with Ca/Mg/K salts) |
| structure | File | |
| classes | List of String, delimiter: , | GABAB Agonist; Endogenous GHB receptor agonist |
| mechanism | String | Agonist at the metabotropic GABAB receptor and the endogenous γ-hydroxybutyrate (GHB) receptor. Produces deep sleep with increased slow-wave architecture, suppression of REM intrusion, and cataplexy reduction. |
| uses | String | '"`UNIQ--vote-00000717-QINU`"', '"`UNIQ--vote-00000718-QINU`"', '"`UNIQ--vote-00000719-QINU`"' |
| starting_dose | String | 2.25 g at bedtime + 2.25 g 2.5–4 h later; titrate weekly to 6–9 g/night total |
| preparations | String | 0.5 g/mL oral solution |
| fda_max | String | 9 g/night |
| pill_id | Text | |
| routes | List of String, delimiter: , | Oral (must be taken in bed; effects within minutes) |
| onset | String | 15–30 min (fasting) |
| duration | String | ~3 h per dose (twice-nightly schedule required) |
| halflife | String | 30–60 min |
| bioavailability | String | ~25% (high first-pass) |
| pregnancy | String | Category C |
| legal | String | Schedule III; REMS-restricted (Schedule I if outside the pharmaceutical channel, same molecule as illicit GHB) |