Page values for "Symbyax"
From Pharmacopedia
More actions
"Medicines" values
1 row is stored for this page| Field | Field type | Value |
|---|---|---|
| generic | String | Olanzapine / Fluoxetine |
| brand | String | Symbyax |
| structure | File | |
| classes | List of String, delimiter: , | [[:Category:Neuroleptics|Atypical neuroleptic (olanzapine)]] • [[:Category:Antidepressants|Antidepressant (fluoxetine • SSRI)]] • [[:Category:Mood_stabilizers|Mood stabilizer]] • [[:Category:Fixed-dose_combinations|Fixed-dose combination]] |
| mechanism | String | '"`UNIQ--vote-00001549-QINU`"' Metabolic effects (weight gain, dyslipidemia, glucose dysregulation) dominate the long-term tolerability profile; routine metabolic monitoring is standard'"`UNIQ--ref-0000154A-QINU`"'. |
| uses | String | '"`UNIQ--vote-0000154B-QINU`"', '"`UNIQ--vote-0000154C-QINU`"' |
| starting_dose | String | 6/25 mg PO once daily in the evening; titrate within range 3/25 to 18/75 mg by clinical response and tolerability |
| preparations | String | Capsules: 3/25, 6/25, 6/50, 12/25, 12/50 mg olanzapine/fluoxetine |
| fda_max | String | 18 mg olanzapine / 75 mg fluoxetine per day |
| pill_id | Text | |
| routes | List of String, delimiter: , | Oral |
| onset | String | Mood improvement at 1-3 weeks; full effect 4-6 weeks |
| duration | String | 24 hours |
| halflife | String | Olanzapine ~30 hours; fluoxetine 1-4 days (norfluoxetine 7-15 days)'"`UNIQ--ref-0000154D-QINU`"' |
| bioavailability | String | Olanzapine 60% (oral); fluoxetine high (oral)'"`UNIQ--ref-0000154E-QINU`"' |
| pregnancy | String | Limited data; fluoxetine has reassuring data but olanzapine carries metabolic-syndrome and gestational diabetes signals.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> |
| legal | String | [[USLegal:Prescription only|Rx-only]] in US. Carries the '''antidepressant Boxed Warning''' for suicidality in children/adolescents/young adults and the atypical-neuroleptic '''Boxed Warning''' for increased mortality in elderly dementia patients'"`UNIQ--ref-0000154F-QINU`"' |