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Page values for "Torsemide"

From Pharmacopedia
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"Medicines" values

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FieldField typeValue
genericStringTorsemide
brandStringDemadex, Soaanz
structureFile
classesList of String, delimiter: ,[[:Category:Loop_diuretics|Loop diuretic]]
mechanismString'"`UNIQ--vote-00000B40-QINU`"' The TRANSFORM-HF trial (2023) found no all-cause mortality difference between torsemide and furosemide in heart failure, although torsemide remains pharmacologically preferred where furosemide oral absorption is unreliable'"`UNIQ--ref-00000B41-QINU`"'.
usesString'"`UNIQ--vote-00000B42-QINU`"', '"`UNIQ--vote-00000B43-QINU`"', '"`UNIQ--vote-00000B44-QINU`"', '"`UNIQ--vote-00000B45-QINU`"'
starting_doseString10-20 mg PO/IV once daily; titrate by clinical response. 1:1 IV to PO conversion (unlike furosemide's 1:2)
preparationsString5, 10, 20, 100 mg tablets; 10 mg/mL IV
fda_maxString200 mg/d typical practical ceiling
pill_idText
routesList of String, delimiter: ,Oral IV
onsetStringPO 1 hour; IV 10 minutes
durationString6-8 hours
halflifeString3-4 hours (similar between PO and IV due to high oral bioavailability)'"`UNIQ--ref-00000B46-QINU`"'
bioavailabilityString~80% (oral; predictable absorption — a substantive practical advantage over furosemide whose oral absorption is 10-100% variable)'"`UNIQ--ref-00000B47-QINU`"'
pregnancyStringAvoid where possible; class concerns as for other loop diuretics.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup>
legalString[[USLegal:Prescription only|Rx-only]] in US