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Medicines (732)

Medicines > classes: [[:Category:Second-generation neuroleptics|Second-generation (atypical) neuroleptic]]

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Seroquel (1)

Dopamine D2 and serotonin 5-HT2A receptor antagonist'"`UNIQ--ref-0000008D-QINU`"' '"`UNIQ--vote-0000008E-QINU`"' (1)

'"`UNIQ--vote-0000008F-QINU`"', '"`UNIQ--vote-00000090-QINU`"', '"`UNIQ--vote-00000091-QINU`"', '"`UNIQ--vote-00000092-QINU`"' (1)

25 mg (schizophrenia, immediate-release); 50 mg (bipolar mania, immediate-release); 50 mg (Seroquel XR, schizophrenia or bipolar) (1)

25 mg, 50 mg, 100 mg, 200 mg, 300 mg, 400 mg immediate-release tablets; 50 mg, 150 mg, 200 mg, 300 mg, 400 mg extended-release tablets (Seroquel XR) (1)

Oral (1)

30-60 min (sedation); days to weeks (neuroleptic effect) (1)

6-8 h (immediate-release); 24 h (extended-release) (1)

~6 h (parent compound, immediate-release); ~9-12 h (active metabolite N-desalkylquetiapine, also called norquetiapine) (1)

Tablet ~100% relative to oral solution; extensive first-pass metabolism (1)

Pregnancy categories were retired by FDA in 2015. Quetiapine has reassuring active-comparator cohort data without consistent teratogenic signal; among the preferred neuroleptics when treatment is clinically necessary in pregnancy. See pregnancy_details for the full citation set. (1)

[[USLegal:Prescription only|Prescription only]]; not a controlled substance (1)

Showing below up to 1 result in range #1 to #1.

Q

Quetiapine

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