Mixed amphetamine salts: Difference between revisions
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MDElliottMD (talk | contribs) Pharmacopedia: add <pharmaInteractions/> |
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| starting_dose = 2.5 mg IR, 5 mg XR, or 12.5mg Mydayis | | starting_dose = 2.5 mg IR, 5 mg XR, or 12.5mg Mydayis | ||
| preparations = IR tabs 5, 7.5, 10, 12.5, 15, 20, 30 mg; XR caps 5, 10, 15, 20, 25, 30 mg; Mydayis caps 12.5, 25, 37.5, 50 mg | | preparations = IR tabs 5, 7.5, 10, 12.5, 15, 20, 30 mg; XR caps 5, 10, 15, 20, 25, 30 mg; Mydayis caps 12.5, 25, 37.5, 50 mg | ||
| fda_max = | | fda_max = XR = 40 or 60 mg/d; IR = 40 or 60 mg/d<ref name="carlat">https://www.thecarlatreport.com/articles/4464-stimulant-dosing-limits</ref> | ||
| routes = Oral | | routes = Oral | ||
| onset = IR: 30–60 min; XR: 1–2 h to peak effect | | onset = IR: 30–60 min; XR: 1–2 h to peak effect | ||
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* <effect ref="withdrawal" author="MDElliottMD">Low motivation, low mood, hypersomnia, increased appetite on abrupt discontinuation.</effect> | * <effect ref="withdrawal" author="MDElliottMD">Low motivation, low mood, hypersomnia, increased appetite on abrupt discontinuation.</effect> | ||
* <effect ref="urinary-retention" author="MDElliottMD">Difficult/slow urination</effect> | * <effect ref="urinary-retention" author="MDElliottMD">Difficult/slow urination</effect> | ||
<effect ref="focus-intensification"/> | |||
<effect ref="appetite-suppression"/> | |||
<effect ref="alertness"/> | |||
<effect ref="executive-functioning"/> | |||
| pk_absorption = Excellent oral bioavailability — sources report ">75%" to "~90%". Food does not significantly affect total absorption but can delay peak concentration. | | pk_absorption = Excellent oral bioavailability — sources report ">75%" to "~90%". Food does not significantly affect total absorption but can delay peak concentration. | ||
| pk_distribution = Volume of distribution ~4 L/kg; plasma protein binding less than 20%. Crosses the blood–brain barrier and placenta. | | pk_distribution = Volume of distribution ~4 L/kg; plasma protein binding less than 20%. Crosses the blood–brain barrier and placenta. | ||
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| references = | | references = | ||
}} | }} | ||
[[Category:Stimulants & Wake-Promoting Agents]] | |||
[[Category:Amphetamines]] | |||