Caffeine: Difference between revisions
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Add Pendell's corner (Dynamis) |
MDElliottMD (talk | contribs) Recategorize: Stimulants -> Psychostimulants |
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{{PendellsCorner | {{PendellsCorner | ||
| quote = | | quote = Caffeine is a central nervous system stimulant, a cardiac stimulant, a respiratory stimulant, and a diuretic. Caffeine is addictive. Withdrawal symptoms typically include irritability, fatigue, and headaches, sometimes severe. | ||
| volume = Dynamis | | volume = Dynamis | ||
| | | page = 29 | ||
}} | }} | ||
[[Category: | [[Category:Psychostimulants]] | ||
[[Category:Xanthines]] | [[Category:Xanthines]] | ||
[[Category:Psychostimulants]] | [[Category:Psychostimulants]] | ||
Latest revision as of 10:50, 17 May 2026
Xanthine, Stimulant
Caffeine
Experience
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No clinical reports yet
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Problems
No problems yet. Be the first to suggest one.
+ Add a problemTitration strategies
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Effects
No effects listed yet. Be the first to suggest one.
Interactions
Pharmacogenomic + mechanism interactions
Pharmacokinetic mechanismSubstrate / metabolism relationships from primary literature
FDA Drug Interactions Table: sensitive index substrate of CYP1A2.
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Clinical relevance: does this interaction matter in practice?trivialcritical
Mechanism description, if it needs work:
Is this row worth surfacing?
Your own experience with this combination:
Experience (1 a little, 5 a lot)
Outcome (-100 worst, +100 best)
Inferred from pharmacokinetic dataMaterialised by the inference engine; provenance shown per row
Fluvoxamine inhibits CYP1A2 (inhibitor_strong, intensity 90); Caffeine is a substrate_major of CYP1A2 (intensity 80). Derived: Caffeine exposure raised.
Inferred via Enzyme:CYP1A2 (exposure raised)
Rate this interaction. Reports are anonymous and help curate the page.
Clinical relevance: does this interaction matter in practice?trivialcritical
Confidence in this inference: is the inferred magnitude sound?overstatedsound
Mechanism description, if it needs work:
Is this row worth surfacing?
Your own experience with this combination:
Experience (1 a little, 5 a lot)
Outcome (-100 worst, +100 best)
Patient experience
No patient-experience reports yet.
Relevant anecdote
No anecdotes yet. Share a relevant one.
Relevant Literature
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Summary
Classes
Xanthine, Stimulant
Pharmacy
Pharmacology
Purported mechanism
Adenosine receptor antagonist
“Pendell's corner
Caffeine is a central nervous system stimulant, a cardiac stimulant, a respiratory stimulant, and a diuretic. Caffeine is addictive. Withdrawal symptoms typically include irritability, fatigue, and headaches, sometimes severe.
— Dale Pendell, Pharmako/Dynamis, p. 29