Coca: Difference between revisions

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| routes = Oral (leaf, buccal); refined cocaine has its own profile

| mechanism = Primary alkaloid is cocaine, a tropane that blocks reuptake of dopamine and norepinephrine (and serotonin). At low oral doses from leaf chewing, the slow release favors NE-mediated alertness over DA-mediated euphoria.

| intro = Coca is the leaf of ''Erythroxylum coca'' (and the related ''E. novogranatense''), cultivated for at least 5,000 years across the Andes. Two ounces of dried leaves (a day's traditional ration) contain ~600 mg cocaine — biologically meaningful, but the leaf-chewing route produces a steady alertness rather than the euphoric spike of refined cocaine. Also a nutrient source: 100 g coca leaf = 300 calories + 18.9 g protein + 100% RDA Ca/Fe/P/B2.

| intro = Coca is the leaf of ''Erythroxylum coca'' (and the related ''E. novogranatense''), cultivated for at least 5,000 years across the Andes. Two ounces of dried leaves (a day's traditional ration) contain ~600 mg cocaine, biologically meaningful, but the leaf-chewing route produces a steady alertness rather than the euphoric spike of refined cocaine. Also a nutrient source: 100 g coca leaf = 300 calories + 18.9 g protein + 100% RDA Ca/Fe/P/B2.

| legal = Leaves legal in Bolivia, Peru, Colombia; cocaine internationally controlled

| seealso = [[Cocaine]], [[Amphetamine]]

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[[Category:Excitantia]]

[[Category:~~Plant Medicines~~]]

[[Category:Plants]]

[[Category:Medicines]]

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