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Pimozide: Difference between revisions

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Category taxonomy (#23): retag to house-compliant neuroleptic categories
 
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{{MedTemplate
{{MedTemplate
| generic           = Pimozide
| generic           = Pimozide
| brand             = Orap
| brand             = Orap
| classes           = Antipsychotic, Neuroleptic
| structure          =
| mechanism         = Diphenylbutylpiperidine D2 antagonist
| classes           = Antipsychotic, Neuroleptic
| mechanism         = Diphenylbutylpiperidine D2 antagonist
| uses              =
| starting_dose      =
| preparations      =
| fda_max          =
| routes            =
| onset              =
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| halflife          =
| bioavailability    =
| pregnancy          =
| legal              =
| intro              =
| pharmacokinetics  =
| pharmacodynamics  =
| indications        =
| dosing            =
| effects            =
| interactions      = <pharmaInteractions/>
| pregnancy_details  =
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[[Category:First-generation neuroleptics]]
[[Category:Neuroleptics]]
[[Category:Neuroleptics]]
 
[[Category:Diphenylbutylpiperidines]]

Latest revision as of 14:41, 22 May 2026

Antipsychotic, Neuroleptic
Pimozide
Orap

Experience

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Problems

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Titration strategies

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Effects

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Interactions

Pharmacogenomic + mechanism interactions2 edges
Pharmacogenomic guideline recommendationsCPIC and Dutch Pharmacogenetics Working Group clinical guidelines
Phenotype:CYP2D6 poor metabolizer dose reduce 50 DPWG 60 / 100
DPWG guideline: Patients who are CYP2D6 intermediate metabolizers should be given no more than 80% of the standard maximum dose of pimozide while patients who are CYP2D6 poor metabolizers should be given no more than 50% of the standard maximum dose.
Phenotype:CYP2D6 intermediate metabolizer dose reduce 50 DPWG 60 / 100
DPWG guideline: Patients who are CYP2D6 intermediate metabolizers should be given no more than 80% of the standard maximum dose of pimozide while patients who are CYP2D6 poor metabolizers should be given no more than 50% of the standard maximum dose.

Patient experience

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Relevant Literature

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Summary
Classes
Antipsychotic, Neuroleptic
Common uses
Pharmacy
Pharmacology
Purported mechanism
Diphenylbutylpiperidine D2 antagonist