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{{MedTemplate
{{MedTemplate
| generic           = MET
| generic           = MET
| classes           = Research material, Tryptamine, Classic Psychedelic
| brand              =
| mechanism         = 5-HT2A agonist
| structure          =
| classes           = Research material, Tryptamine, Classic Psychedelic
| mechanism         = 5-HT2A agonist
| uses              =
| starting_dose      =
| preparations      =
| fda_max          =
| routes            =
| onset              =
| duration          =
| halflife          =
| bioavailability    =
| pregnancy          =
| legal              =
| intro              =
| pharmacokinetics  =
| pharmacodynamics  =
| indications        =
| dosing            =
<titration slug="erowid-dose-multi-route" author="erowid-claude"
title="Multi-route dose ladders (Erowid, very tentative)">
Erowid's dosage documentation for MET<ref name="erowid-met-dose">
Erowid. MET Dosage. Erowid.org.
https://www.erowid.org/chemicals/met/met_dose.shtml.
Accessed 2026-05-25.</ref> is marked "very tentative" by Erowid,
given limited reports. The following tiers are reported:
 
'''Oral:'''
* Light: 60-120 mg; Common: 80-150 mg; Strong: 150+ mg
* (Threshold not characterized; timing not provided)
 
'''Vaporized:'''
* Threshold: ~8 mg; Light: 10-20 mg; Common: 15-30 mg; Strong: 30-40+ mg
 
'''Insufflated:'''
* Light: 10-20 mg; Common: 15-25 mg
 
'''Intramuscular:'''
* Common: 10-30 mg; Strong: 30-50+ mg
 
The wide disparity between oral (60+ mg) and vaporized (8+ mg) tiers
is a pharmacokinetic feature of the tryptamine class generally, and
is particularly marked for MET. Erowid's own tentative qualification
should be reflected in any presentation of these figures.
</titration>
| effects            =
| interactions      = <pharmaInteractions/>
| pregnancy_details  =
| monitoring        =
| counseling        =
| anecdotes          =
| seealso            =
| references        =
}}
}}
[[Category:Classic_Psychedelics]]


[[Category:Research chemicals]]
[[Category:Tryptamines]]
[[Category:Classical Psychedelics (Serotonergic)]]
[[Category:Psychedelics]]

Latest revision as of 04:21, 26 May 2026

Research material, Tryptamine, Classic Psychedelic
MET

Experience

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Problems

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Titration strategies

Multi-route dose ladders (Erowid, very tentative)0
Erowid's dosage documentation for MET[1] is marked "very tentative" by Erowid,

given limited reports. The following tiers are reported:

Oral:

  • Light: 60-120 mg; Common: 80-150 mg; Strong: 150+ mg
  • (Threshold not characterized; timing not provided)

Vaporized:

  • Threshold: ~8 mg; Light: 10-20 mg; Common: 15-30 mg; Strong: 30-40+ mg

Insufflated:

  • Light: 10-20 mg; Common: 15-25 mg

Intramuscular:

  • Common: 10-30 mg; Strong: 30-50+ mg

The wide disparity between oral (60+ mg) and vaporized (8+ mg) tiers is a pharmacokinetic feature of the tryptamine class generally, and is particularly marked for MET. Erowid's own tentative qualification

should be reflected in any presentation of these figures.

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Effects

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Interactions

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Relevant Literature

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Summary
Classes
Research material, Tryptamine, Classic Psychedelic
Common uses
Pharmacy
Pharmacology
Purported mechanism
5-HT2A agonist
  1. Erowid. MET Dosage. Erowid.org. https://www.erowid.org/chemicals/met/met_dose.shtml. Accessed 2026-05-25.