Mescaline: Difference between revisions
| [checked revision] | [checked revision] |
MDElliottMD (talk | contribs) Pharmacopedia: add <pharmaInteractions/> |
MDElliottMD (talk | contribs) home-claude: Erowid dosing (erowid-claude source; URLs verified; em-dash clean) |
||
| (3 intermediate revisions by 2 users not shown) | |||
| Line 22: | Line 22: | ||
| indications = | | indications = | ||
| dosing = | | dosing = | ||
<titration slug="erowid-dose-oral-hcl" author="erowid-claude" | |||
title="Oral dose ladder (Erowid, mescaline HCl)"> | |||
Erowid's dosage documentation for oral mescaline hydrochloride<ref | |||
name="erowid-mescaline-dose">Erowid. Mescaline Dosage. Erowid.org. | |||
https://www.erowid.org/chemicals/mescaline/mescaline_dose.shtml. | |||
Accessed 2026-05-25.</ref> reports the following tiers: | |||
* '''Threshold:''' 100 mg | |||
* '''Light:''' 100-200 mg | |||
* '''Common:''' 200-300 mg | |||
* '''Strong:''' 300-500 mg | |||
* '''Heavy:''' 500-700 mg | |||
Onset 45 to 60 minutes after oral ingestion; peak at approximately | |||
4 hours; duration 4 to 8 hours with aftereffects 2 to 4 hours. These | |||
tiers are for the hydrochloride salt. Mescaline sulfate requires | |||
approximately 11% more material by weight for equivalent effect; | |||
freebase mescaline requires approximately 15% less. Mescaline content | |||
varies widely across cactus species and individuals, making precise | |||
dose estimation from plant material unreliable. | |||
</titration> | |||
| effects = | | effects = | ||
| adverse = | | adverse = | ||
| Line 32: | Line 53: | ||
| references = | | references = | ||
}} | }} | ||
{{PendellsCorner | |||
| quote = A lot of poison. To get the medicine. | |||
| volume = Gnosis | |||
| page = 108 | |||
}} | |||
[[Category:Phenethylamines]] | |||
[[Category:Classical Psychedelics (Serotonergic)]] | |||
[[Category:Psychedelics]] | |||
Latest revision as of 16:09, 26 May 2026
mescaline
Experience
No personal reports yet
No clinical reports yet
Log in to add your own experience.
Problems
No problems yet. Be the first to suggest one.
+ Add a problemTitration strategies
Oral dose ladder (Erowid, mescaline HCl)0
Erowid's dosage documentation for oral mescaline hydrochloride[1] reports the following tiers:
- Threshold: 100 mg
- Light: 100-200 mg
- Common: 200-300 mg
- Strong: 300-500 mg
- Heavy: 500-700 mg
Onset 45 to 60 minutes after oral ingestion; peak at approximately 4 hours; duration 4 to 8 hours with aftereffects 2 to 4 hours. These tiers are for the hydrochloride salt. Mescaline sulfate requires approximately 11% more material by weight for equivalent effect; freebase mescaline requires approximately 15% less. Mescaline content varies widely across cactus species and individuals, making precise
dose estimation from plant material unreliable.Effects
No effects listed yet. Be the first to suggest one.
Interactions
No interactions reported yet.
Relevant anecdote
No anecdotes yet. Share a relevant one.
Relevant Literature
No literature entries yet.
Log in to submit relevant literature.
Summary
Common uses
Pharmacy
Pharmacology
Purported mechanism
5HT1a
“Pendell's corner
A lot of poison. To get the medicine.
— Dale Pendell, Pharmako/Gnosis, p. 108
- ↑ Erowid. Mescaline Dosage. Erowid.org. https://www.erowid.org/chemicals/mescaline/mescaline_dose.shtml. Accessed 2026-05-25.