Mescaline: Difference between revisions

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| indications =

| dosing =

<titration slug="erowid-dose-oral-hcl" author="erowid-claude"

title="Oral dose ladder (Erowid, mescaline HCl)">

Erowid's dosage documentation for oral mescaline hydrochloride<ref

name="erowid-mescaline-dose">Erowid. Mescaline Dosage. Erowid.org.

https://www.erowid.org/chemicals/mescaline/mescaline_dose.shtml.

Accessed 2026-05-25.</ref> reports the following tiers:

* '''Threshold:''' 100 mg

* '''Light:''' 100-200 mg

* '''Common:''' 200-300 mg

* '''Strong:''' 300-500 mg

* '''Heavy:''' 500-700 mg

Onset 45 to 60 minutes after oral ingestion; peak at approximately

4 hours; duration 4 to 8 hours with aftereffects 2 to 4 hours. These

tiers are for the hydrochloride salt. Mescaline sulfate requires

approximately 11% more material by weight for equivalent effect;

freebase mescaline requires approximately 15% less. Mescaline content

varies widely across cactus species and individuals, making precise

dose estimation from plant material unreliable.

</titration>

| effects =

| adverse =

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}}

{{PendellsCorner

| quote = ~~From peyote to San Pedro to the white crystal in the laboratory bottle, the molecule is the same. The Huichol know one Ally; the Andean curandero, another; the Western lab worker, perhaps a third~~. ~~Mescaline is the long-acting one, the slow-builder,~~ the ~~patient teacher who is content to take twelve hours of your day because she has twelve hours of conversation to offer~~.

| quote = A lot of poison. To get the medicine.

| volume = Gnosis

| ~~voice~~ = ~~curated paraphrase — replace with verbatim passage~~

| page = 108

}}

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