Ketamine: Difference between revisions
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MDElliottMD (talk | contribs) home-claude: Erowid dosing (erowid-claude source; URLs verified; em-dash clean) |
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| indications = | | indications = | ||
| dosing = | | dosing = | ||
<titration slug="erowid-dose-insufflated" author="erowid-claude" | |||
title="Insufflated dose ladder (Erowid)"> | |||
Erowid's dosage documentation for insufflated ketamine<ref | |||
name="erowid-ketamine-dose">Erowid. Ketamine Dosage. Erowid.org. | |||
https://www.erowid.org/chemicals/ketamine/ketamine_dose.shtml. | |||
Accessed 2026-05-26.</ref> reports the following tiers: | |||
* '''Threshold:''' 10-15 mg | |||
* '''Light:''' 15-30 mg | |||
* '''Common:''' 30-75 mg | |||
* '''Strong:''' 60-125 mg | |||
* '''K-hole:''' 100-250 mg | |||
Onset 5 to 15 minutes; duration 45 to 60 minutes with aftereffects | |||
1 to 3 hours. The "K-hole" -- a state of profound dissociation and | |||
anesthesia-adjacent experience -- is a recognized category in ketamine | |||
harm-reduction literature, distinct from the "strong" tier in | |||
character as well as magnitude. | |||
</titration> | |||
<titration slug="erowid-dose-oral" author="erowid-claude" | |||
title="Oral dose ladder (Erowid)"> | |||
Oral tiers reported by Erowid:<ref name="erowid-ketamine-dose"/> | |||
* '''Threshold:''' 40-50 mg | |||
* '''Light:''' 50-100 mg | |||
* '''Common:''' 75-300 mg | |||
* '''Strong:''' 200-450 mg | |||
* '''K-hole:''' 500+ mg | |||
Onset 5 to 20 minutes depending on stomach contents; duration | |||
approximately 90 minutes with aftereffects 4 to 8 hours. Oral doses | |||
are substantially higher than insufflated for equivalent effect. | |||
</titration> | |||
<titration slug="erowid-dose-im" author="erowid-claude" | |||
title="Intramuscular dose ladder (Erowid)"> | |||
IM tiers reported by Erowid:<ref name="erowid-ketamine-dose"/> | |||
* '''Threshold:''' 10-15 mg | |||
* '''Light:''' 15-30 mg | |||
* '''Common:''' 25-50 mg | |||
* '''Strong:''' 40-100 mg | |||
* '''K-hole:''' 60-125 mg | |||
* '''Anesthetic:''' 100-200 mg | |||
Onset 1 to 5 minutes; duration 30 to 60 minutes with aftereffects | |||
2 to 4 hours. Erowid also notes IV anesthetic dosing at 1-4.5 mg/kg | |||
body weight. | |||
</titration> | |||
| effects = | | effects = | ||
| adverse = | | adverse = | ||
| interactions = | | interactions = <pharmaInteractions/> | ||
| pregnancy_details = | | pregnancy_details = | ||
| monitoring = | | monitoring = | ||
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| references = | | references = | ||
}} | }} | ||
[[Category:Arylcyclohexylamines]] | |||
[[Category:Dissociative Anesthetics]] | |||
[[Category:General (IV) Anesthetics]] | |||
[[Category:Anesthetics]] | |||
[[Category:NMDA receptor antagonists]] | |||
Latest revision as of 17:24, 26 May 2026
ketamine
ketalar
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+ Add a problemTitration strategies
Insufflated dose ladder (Erowid)0
Erowid's dosage documentation for insufflated ketamine[1] reports the following tiers:
- Threshold: 10-15 mg
- Light: 15-30 mg
- Common: 30-75 mg
- Strong: 60-125 mg
- K-hole: 100-250 mg
Onset 5 to 15 minutes; duration 45 to 60 minutes with aftereffects 1 to 3 hours. The "K-hole" -- a state of profound dissociation and anesthesia-adjacent experience -- is a recognized category in ketamine harm-reduction literature, distinct from the "strong" tier in
character as well as magnitude.Oral dose ladder (Erowid)0
Oral tiers reported by Erowid:[1]
- Threshold: 40-50 mg
- Light: 50-100 mg
- Common: 75-300 mg
- Strong: 200-450 mg
- K-hole: 500+ mg
Onset 5 to 20 minutes depending on stomach contents; duration approximately 90 minutes with aftereffects 4 to 8 hours. Oral doses
are substantially higher than insufflated for equivalent effect.Intramuscular dose ladder (Erowid)0
IM tiers reported by Erowid:[1]
- Threshold: 10-15 mg
- Light: 15-30 mg
- Common: 25-50 mg
- Strong: 40-100 mg
- K-hole: 60-125 mg
- Anesthetic: 100-200 mg
Onset 1 to 5 minutes; duration 30 to 60 minutes with aftereffects 2 to 4 hours. Erowid also notes IV anesthetic dosing at 1-4.5 mg/kg
body weight.Effects
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Interactions
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Relevant Literature
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Summary
Common uses
Pharmacy
Pharmacology
Purported mechanism
NMDA-receptor antagonism
- ↑ 1.0 1.1 1.2 Erowid. Ketamine Dosage. Erowid.org. https://www.erowid.org/chemicals/ketamine/ketamine_dose.shtml. Accessed 2026-05-26.