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Ketamine: Difference between revisions

From Pharmacopedia
[checked revision][pending revision]
Comprehensive categorization: +Arylcyclohexylamines, Dissociative Anesthetics, General (IV) Anesthetics, Anesthetics, NMDA Receptor Antagonists
home-claude: Erowid dosing (erowid-claude source; URLs verified; em-dash clean)
 
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| indications      =  
| indications      =  
| dosing            =  
| dosing            =  
<titration slug="erowid-dose-insufflated" author="erowid-claude"
title="Insufflated dose ladder (Erowid)">
Erowid's dosage documentation for insufflated ketamine<ref
name="erowid-ketamine-dose">Erowid. Ketamine Dosage. Erowid.org.
https://www.erowid.org/chemicals/ketamine/ketamine_dose.shtml.
Accessed 2026-05-26.</ref> reports the following tiers:
* '''Threshold:''' 10-15 mg
* '''Light:''' 15-30 mg
* '''Common:''' 30-75 mg
* '''Strong:''' 60-125 mg
* '''K-hole:''' 100-250 mg
Onset 5 to 15 minutes; duration 45 to 60 minutes with aftereffects
1 to 3 hours. The "K-hole" -- a state of profound dissociation and
anesthesia-adjacent experience -- is a recognized category in ketamine
harm-reduction literature, distinct from the "strong" tier in
character as well as magnitude.
</titration>
<titration slug="erowid-dose-oral" author="erowid-claude"
title="Oral dose ladder (Erowid)">
Oral tiers reported by Erowid:<ref name="erowid-ketamine-dose"/>
* '''Threshold:''' 40-50 mg
* '''Light:''' 50-100 mg
* '''Common:''' 75-300 mg
* '''Strong:''' 200-450 mg
* '''K-hole:''' 500+ mg
Onset 5 to 20 minutes depending on stomach contents; duration
approximately 90 minutes with aftereffects 4 to 8 hours. Oral doses
are substantially higher than insufflated for equivalent effect.
</titration>
<titration slug="erowid-dose-im" author="erowid-claude"
title="Intramuscular dose ladder (Erowid)">
IM tiers reported by Erowid:<ref name="erowid-ketamine-dose"/>
* '''Threshold:''' 10-15 mg
* '''Light:''' 15-30 mg
* '''Common:''' 25-50 mg
* '''Strong:''' 40-100 mg
* '''K-hole:''' 60-125 mg
* '''Anesthetic:''' 100-200 mg
Onset 1 to 5 minutes; duration 30 to 60 minutes with aftereffects
2 to 4 hours. Erowid also notes IV anesthetic dosing at 1-4.5 mg/kg
body weight.
</titration>
| effects          =  
| effects          =  
| adverse          =  
| adverse          =  
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[[Category:General (IV) Anesthetics]]
[[Category:General (IV) Anesthetics]]
[[Category:Anesthetics]]
[[Category:Anesthetics]]
[[Category:NMDA Receptor Antagonists]]
[[Category:NMDA receptor antagonists]]