5-MeO-DMT: Difference between revisions
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| indications = | | indications = | ||
| dosing = | | dosing = | ||
<titration slug="erowid-dose-smoked" author="erowid-claude" | |||
title="Smoked/vaporized dose ladder (Erowid)"> | |||
Erowid's dosage documentation for smoked or vaporized 5-MeO-DMT<ref | |||
name="erowid-5meodmt-dose">Erowid. 5-MeO-DMT Dosage. Erowid.org. | |||
https://www.erowid.org/chemicals/5meo_dmt/5meo_dmt_dose.shtml. | |||
Accessed 2026-05-25.</ref> reports the following tiers: | |||
* '''Threshold:''' 1-2 mg | |||
* '''Light:''' 2-5 mg | |||
* '''Common:''' 5-10 mg | |||
* '''Strong:''' 10-20 mg | |||
Onset is within 30 seconds to 1 minute after inhalation; peak at 1 to | |||
15 minutes; total duration approximately 30 minutes with aftereffects | |||
lasting up to 1 hour. The brevity and abruptness of the smoked route | |||
distinguishes 5-MeO-DMT sharply from the oral tryptamines. Erowid | |||
emphasizes that individual response varies widely and overwhelmingly | |||
intense experiences have been reported at doses within the common range. | |||
</titration> | |||
<titration slug="erowid-dose-insufflated" author="erowid-claude" | |||
title="Insufflated dose ladder (Erowid)"> | |||
Insufflated (intranasal) dose tiers reported by Erowid:<ref | |||
name="erowid-5meodmt-dose"/> | |||
* '''Threshold:''' 3-5 mg | |||
* '''Light:''' 5-10 mg | |||
* '''Common:''' 8-15 mg | |||
* '''Strong:''' 10-25 mg | |||
Onset approximately 5 minutes after insufflation; peak at 10 to 30 | |||
minutes; duration 30 to 45 minutes with aftereffects up to 3 hours. | |||
Doses are higher than smoked tiers but the experience profile is | |||
broadly similar. | |||
</titration> | |||
| effects = | | effects = | ||
| interactions = <pharmaInteractions/> | | interactions = <pharmaInteractions/> | ||
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[[Category:Research | {{PendellsCorner | ||
| quote = There is a peaceful quality, a great spaciousness and stillness. There is patterning and geometric imagery, but it doesn't buzz the way DMT does. ... Mixtures of the two tryptamines are called "the jaguar twins." The 5-MeO-DMT seems to add heart, an empathogenic connectedness. | |||
| volume = Gnosis | |||
| page = 223 | |||
}} | |||
[[Category:Research chemicals]] | |||
[[Category:Tryptamines]] | [[Category:Tryptamines]] | ||
[[Category: | [[Category:Classical Psychedelics (Serotonergic)]] | ||
[[Category:Psychedelics]] | |||
Latest revision as of 04:21, 26 May 2026
Research material, Tryptamine, Classic Psychedelic
5-MeO-DMT
Experience
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Problems
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+ Add a problemTitration strategies
Smoked/vaporized dose ladder (Erowid)0
Erowid's dosage documentation for smoked or vaporized 5-MeO-DMT[1] reports the following tiers:
- Threshold: 1-2 mg
- Light: 2-5 mg
- Common: 5-10 mg
- Strong: 10-20 mg
Onset is within 30 seconds to 1 minute after inhalation; peak at 1 to 15 minutes; total duration approximately 30 minutes with aftereffects lasting up to 1 hour. The brevity and abruptness of the smoked route distinguishes 5-MeO-DMT sharply from the oral tryptamines. Erowid emphasizes that individual response varies widely and overwhelmingly
intense experiences have been reported at doses within the common range.Insufflated dose ladder (Erowid)0
Insufflated (intranasal) dose tiers reported by Erowid:[1]
- Threshold: 3-5 mg
- Light: 5-10 mg
- Common: 8-15 mg
- Strong: 10-25 mg
Onset approximately 5 minutes after insufflation; peak at 10 to 30 minutes; duration 30 to 45 minutes with aftereffects up to 3 hours. Doses are higher than smoked tiers but the experience profile is
broadly similar.Effects
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Interactions
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Relevant anecdote
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Relevant Literature
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Summary
Classes
Research material, Tryptamine, Classic Psychedelic
Common uses
Pharmacy
Pharmacology
Purported mechanism
Potent 5-HT2A agonist; sigma-1 agonist
“Pendell's corner
There is a peaceful quality, a great spaciousness and stillness. There is patterning and geometric imagery, but it doesn't buzz the way DMT does. ... Mixtures of the two tryptamines are called "the jaguar twins." The 5-MeO-DMT seems to add heart, an empathogenic connectedness.
— Dale Pendell, Pharmako/Gnosis, p. 223
- ↑ 1.0 1.1 Erowid. 5-MeO-DMT Dosage. Erowid.org. https://www.erowid.org/chemicals/5meo_dmt/5meo_dmt_dose.shtml. Accessed 2026-05-25.