Coca: Difference between revisions

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| routes = Oral (leaf, buccal); refined cocaine has its own profile

| mechanism = Primary alkaloid is cocaine, a tropane that blocks reuptake of dopamine and norepinephrine (and serotonin). At low oral doses from leaf chewing, the slow release favors NE-mediated alertness over DA-mediated euphoria.

| intro = Coca is the leaf of ''Erythroxylum coca'' (and the related ''E. novogranatense''), cultivated for at least 5,000 years across the Andes. Two ounces of dried leaves (a day's traditional ration) contain ~600 mg cocaine — biologically meaningful, but the leaf-chewing route produces a steady alertness rather than the euphoric spike of refined cocaine. Also a nutrient source: 100 g coca leaf = 300 calories + 18.9 g protein + 100% RDA Ca/Fe/P/B2.

| intro = Coca is the leaf of ''Erythroxylum coca'' (and the related ''E. novogranatense''), cultivated for at least 5,000 years across the Andes. Two ounces of dried leaves (a day's traditional ration) contain ~600 mg cocaine, biologically meaningful, but the leaf-chewing route produces a steady alertness rather than the euphoric spike of refined cocaine. Also a nutrient source: 100 g coca leaf = 300 calories + 18.9 g protein + 100% RDA Ca/Fe/P/B2.

| legal = Leaves legal in Bolivia, Peru, Colombia; cocaine internationally controlled

| seealso = [[Cocaine]], [[Amphetamine]]

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{{PendellsCorner

| quote = ~~The~~ Andes ~~knew~~ the ~~leaf before they knew the kingdoms. Coca was a sacrament before she was~~ a ~~commodity, and the chewer and the prayer were the same act~~. ~~What was extracted from her, what was named cocaine, what was sold in salts and powders — that~~ is a ~~different relationship~~, ~~one that has forgotten~~ the ~~leaf. Coca remembers~~.

| quote = Even in the Andes, the stimulant had a punctuating function. The quid itself is a measure of time, distances measured by the number of chews required to traverse the terrain.

| volume = Dynamis

~~| voice = curated paraphrase — replace with verbatim passage~~

}}

[[Category:Excitantia]]

[[Category:~~Plant Medicines~~]]

[[Category:Plants]]

[[Category:Medicines]]

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