Dextromethorphan: Difference between revisions
From Pharmacopedia
More actions
| [unchecked revision] | [pending revision] |
MDElliottMD (talk | contribs) Auto-created stub |
MDElliottMD (talk | contribs) home-claude: Erowid dosing (erowid-claude source; URLs verified; em-dash clean) |
||
| (7 intermediate revisions by 3 users not shown) | |||
| Line 1: | Line 1: | ||
{{MedTemplate | {{MedTemplate | ||
| generic | | generic = Dextromethorphan | ||
| brand | | brand = DXM | ||
| classes | | structure = | ||
| mechanism | | classes = Dissociative | ||
| mechanism = NMDA antagonist; sigma-1 agonist; serotonin reuptake inhibitor | |||
| uses = | |||
| starting_dose = | |||
| preparations = | |||
| fda_max = | |||
| routes = | |||
| onset = | |||
| duration = | |||
| halflife = | |||
| bioavailability = | |||
| pregnancy = | |||
| legal = | |||
| intro = | |||
| pharmacokinetics = | |||
| pharmacodynamics = | |||
| indications = | |||
| dosing = | |||
<titration slug="erowid-dose-oral" author="erowid-claude" | |||
title="Oral dose ladder (Erowid, HBr salt)"> | |||
Erowid's dosage documentation for oral dextromethorphan hydrobromide<ref | |||
name="erowid-dxm-dose">Erowid. DXM Dosage. Erowid.org. | |||
https://www.erowid.org/chemicals/dxm/dxm_dose.shtml. | |||
Accessed 2026-05-26.</ref> reports the following tiers: | |||
* '''Light:''' 100-200 mg | |||
* '''Common:''' 200-400 mg | |||
* '''Strong:''' 300-600 mg | |||
* '''Heavy:''' 600-1,500 mg | |||
Threshold not characterized. Duration 4 to 8 hours for standard HBr | |||
formulations; 6 to 12 hours for extended-release polistirex | |||
formulations. Erowid notes that doses are affected significantly by | |||
body weight and recommends conservative starting amounts. A critical | |||
harm note: many OTC formulations containing DXM also include | |||
acetaminophen, chlorpheniramine maleate (CPM), guaifenesin, or other | |||
active ingredients that become dangerous at the doses required for | |||
psychoactive DXM effects; use of single-ingredient preparations is | |||
essential for harm reduction. | |||
</titration> | |||
| effects = | |||
| interactions = <pharmaInteractions/> | |||
| pregnancy_details = | |||
| monitoring = | |||
| counseling = | |||
| anecdotes = | |||
| seealso = | |||
| references = | |||
}} | }} | ||
[[Category:Psychedelics]] | |||
[[Category:Dissociatives]] | [[Category:Dissociatives]] | ||
[[Category:Morphinans]] | |||
[[Category:Dissociative Anesthetics]] | |||
[[Category:NMDA receptor antagonists]] | |||