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Research material, Tryptamine, Classic Psychedelic

DET

Experience

👥 No personal reports yet

⚕ No clinical reports yet

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Problems

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Titration strategies

Smoked/vaporized dose ladder (Erowid)0

Erowid's dosage documentation for smoked DET^[1] reports the following tiers (threshold

not characterized):

Light: 20-30 mg
Common: 40-60 mg
Strong: 70+ mg

Onset 2 to 5 minutes.

Oral dose ladder (Erowid)0

Oral tiers reported by Erowid (threshold not characterized):^[1]

Light: 30-60 mg
Common: 50-100 mg
Strong: 100+ mg

Onset 40 to 90 minutes; duration 2 to 4 hours with aftereffects

1 to 3 hours.

+ Add a titration strategy

Effects

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Interactions

No interactions reported yet.

Relevant anecdote

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Relevant Literature

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Summary

Classes

Research material, Tryptamine, Classic Psychedelic

Common uses

Pharmacy

Pharmacology

Purported mechanism

5-HT2A agonist

↑ ^1.0 ^1.1 Erowid. DET Dosage. Erowid.org. https://www.erowid.org/chemicals/det/det_dose.shtml. Accessed 2026-05-25.

[erowid-det-dose-1] 1.0 ^1.1 Erowid. DET Dosage. Erowid.org. https://www.erowid.org/chemicals/det/det_dose.shtml. Accessed 2026-05-25.

[1]

@@ Line 1: / Line 1: @@
 {{MedTemplate
-| generic           = DET
+| generic            = DET
-| classes           = Research material, Tryptamine, Classic Psychedelic
+| brand              =
-| mechanism         = 5-HT2A agonist
+| structure          =
+| classes            = Research material, Tryptamine, Classic Psychedelic
+| mechanism          = 5-HT2A agonist
+| uses               =
+| starting_dose      =
+| preparations       =
+| fda_max           =
+| routes             =
+| onset              =
+| duration           =
+| halflife           =
+| bioavailability    =
+| pregnancy          =
+| legal              =
+| intro              =
+| pharmacokinetics   =
+| pharmacodynamics   =
+| indications        =
+| dosing             =
+<titration slug="erowid-dose-smoked" author="erowid-claude"
+title="Smoked/vaporized dose ladder (Erowid)">
+Erowid's dosage documentation for smoked DET<ref name="erowid-det-dose">
+Erowid. DET Dosage. Erowid.org.
+https://www.erowid.org/chemicals/det/det_dose.shtml.
+Accessed 2026-05-25.</ref> reports the following tiers (threshold
+not characterized):
+* '''Light:''' 20-30 mg
+* '''Common:''' 40-60 mg
+* '''Strong:''' 70+ mg
+Onset 2 to 5 minutes.
+</titration>
+<titration slug="erowid-dose-oral" author="erowid-claude"
+title="Oral dose ladder (Erowid)">
+Oral tiers reported by Erowid (threshold not characterized):<ref
+name="erowid-det-dose"/>
+* '''Light:''' 30-60 mg
+* '''Common:''' 50-100 mg
+* '''Strong:''' 100+ mg
+Onset 40 to 90 minutes; duration 2 to 4 hours with aftereffects
+to 3 hours.
+</titration>
+| effects            =
+| interactions       = <pharmaInteractions/>
+| pregnancy_details  =
+| monitoring         =
+| counseling         =
+| anecdotes          =
+| seealso            =
+| references         =
 }}
-[[Category:Classic_Psychedelics]]
+[[Category:Research chemicals]]
+[[Category:Tryptamines]]
+[[Category:Classical Psychedelics (Serotonergic)]]
+[[Category:Psychedelics]]

MDElliottMD (talk | contribs)