Methoxetamine: Difference between revisions
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| dosing = | | dosing = | ||
<titration slug="erowid-dose-multi-route" author="erowid-claude" | |||
title="Multi-route dose ladders (Erowid, very tentative)"> | |||
Erowid's dosage documentation for methoxetamine (MXE)<ref | |||
name="erowid-mxe-dose">Erowid. Methoxetamine Dosage. Erowid.org. | |||
https://www.erowid.org/chemicals/methoxetamine/methoxetamine_dose.shtml. | |||
Accessed 2026-05-26.</ref> is marked "very tentative" throughout and | |||
notes that "doses reported by different users vary by a large amount." | |||
'''Insufflated:''' | |||
* Threshold: 5-20 mg; Light: 10-50 mg; Common: 20-60 mg; Strong: 25-100+ mg | |||
'''Oral:''' | |||
* Threshold: 8-20 mg; Light: 10-30 mg; Common: 40-60 mg; Strong: 50-100+ mg | |||
'''Sublingual/buccal:''' | |||
* Threshold: 5-10 mg; Light: 8-25 mg; Common: 15-50 mg; Strong: 40-100+ mg | |||
'''Intramuscular:''' | |||
* Threshold: 3-8 mg; Light: 5-20 mg; Common: 15-30 mg; Strong: 20-80+ mg | |||
Timing data are not provided by Erowid. The wide variability between | |||
users (some report strong effects at 50 mg; others minimal at the | |||
same dose) and Erowid's tentative qualifier should be reflected in | |||
any presentation. | |||
</titration> | |||
| effects = | | effects = | ||
| interactions = <pharmaInteractions/> | | interactions = <pharmaInteractions/> | ||
Latest revision as of 17:24, 26 May 2026
Research material, Dissociative
Methoxetamine
Experience
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+ Add a problemTitration strategies
Multi-route dose ladders (Erowid, very tentative)0
Erowid's dosage documentation for methoxetamine (MXE)[1] is marked "very tentative" throughout and
notes that "doses reported by different users vary by a large amount."
Insufflated:
- Threshold: 5-20 mg; Light: 10-50 mg; Common: 20-60 mg; Strong: 25-100+ mg
Oral:
- Threshold: 8-20 mg; Light: 10-30 mg; Common: 40-60 mg; Strong: 50-100+ mg
Sublingual/buccal:
- Threshold: 5-10 mg; Light: 8-25 mg; Common: 15-50 mg; Strong: 40-100+ mg
Intramuscular:
- Threshold: 3-8 mg; Light: 5-20 mg; Common: 15-30 mg; Strong: 20-80+ mg
Timing data are not provided by Erowid. The wide variability between users (some report strong effects at 50 mg; others minimal at the same dose) and Erowid's tentative qualifier should be reflected in
any presentation.Effects
No effects listed yet. Be the first to suggest one.
Interactions
No interactions reported yet.
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Relevant Literature
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Summary
Classes
Research material, Dissociative
Common uses
Pharmacy
Pharmacology
Purported mechanism
NMDA antagonist; SERT inhibitor; sigma-1 agonist
- ↑ Erowid. Methoxetamine Dosage. Erowid.org. https://www.erowid.org/chemicals/methoxetamine/methoxetamine_dose.shtml. Accessed 2026-05-26.