Triazolam: Difference between revisions
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[[Category:Sedative-hypnotics]] | |||
[[Category:Benzodiazepines]] | |||
[[Category:Anxiolytics]] | [[Category:Anxiolytics]] | ||
[[Category:GABAA Positive Allosteric Modulators (General)]] | |||
[[Category:GABAergics]] | |||
Latest revision as of 00:37, 22 May 2026
Benzodiazepine, Sedative-Hypnotic
Triazolam
Halcion
Experience
No personal reports yet
No clinical reports yet
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Problems
No problems yet. Be the first to suggest one.
+ Add a problemTitration strategies
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Effects
No effects listed yet. Be the first to suggest one.
Interactions
Pharmacogenomic + mechanism interactions
Pharmacokinetic mechanismSubstrate / metabolism relationships from primary literature
FDA Drug Interactions Table: sensitive index substrate of CYP3A4.
Rate this interaction. Reports are anonymous and help curate the page.
Clinical relevance: does this interaction matter in practice?trivialcritical
Mechanism description, if it needs work:
Is this row worth surfacing?
Your own experience with this combination:
Experience (1 a little, 5 a lot)
Outcome (-100 worst, +100 best)
Inferred from pharmacokinetic dataMaterialised by the inference engine; provenance shown per row
Clarithromycin inhibits CYP3A4 (inhibitor_strong, intensity 90); Triazolam is a substrate_major of CYP3A4 (intensity 80). Derived: Triazolam exposure raised.
Inferred via Enzyme:CYP3A4 (exposure raised)
Rate this interaction. Reports are anonymous and help curate the page.
Clinical relevance: does this interaction matter in practice?trivialcritical
Confidence in this inference: is the inferred magnitude sound?overstatedsound
Mechanism description, if it needs work:
Is this row worth surfacing?
Your own experience with this combination:
Experience (1 a little, 5 a lot)
Outcome (-100 worst, +100 best)
Itraconazole inhibits CYP3A4 (inhibitor_strong, intensity 90); Triazolam is a substrate_major of CYP3A4 (intensity 80). Derived: Triazolam exposure raised.
Inferred via Enzyme:CYP3A4 (exposure raised)
Rate this interaction. Reports are anonymous and help curate the page.
Clinical relevance: does this interaction matter in practice?trivialcritical
Confidence in this inference: is the inferred magnitude sound?overstatedsound
Mechanism description, if it needs work:
Is this row worth surfacing?
Your own experience with this combination:
Experience (1 a little, 5 a lot)
Outcome (-100 worst, +100 best)
Carbamazepine induces CYP3A4 (inducer_strong, intensity 90); Triazolam is a substrate_major of CYP3A4 (intensity 80). Derived: Triazolam exposure lowered.
Inferred via Enzyme:CYP3A4 (exposure lowered)
Rate this interaction. Reports are anonymous and help curate the page.
Clinical relevance: does this interaction matter in practice?trivialcritical
Confidence in this inference: is the inferred magnitude sound?overstatedsound
Mechanism description, if it needs work:
Is this row worth surfacing?
Your own experience with this combination:
Experience (1 a little, 5 a lot)
Outcome (-100 worst, +100 best)
Phenytoin induces CYP3A4 (inducer_strong, intensity 90); Triazolam is a substrate_major of CYP3A4 (intensity 80). Derived: Triazolam exposure lowered.
Inferred via Enzyme:CYP3A4 (exposure lowered)
Rate this interaction. Reports are anonymous and help curate the page.
Clinical relevance: does this interaction matter in practice?trivialcritical
Confidence in this inference: is the inferred magnitude sound?overstatedsound
Mechanism description, if it needs work:
Is this row worth surfacing?
Your own experience with this combination:
Experience (1 a little, 5 a lot)
Outcome (-100 worst, +100 best)
Rifampin induces CYP3A4 (inducer_strong, intensity 90); Triazolam is a substrate_major of CYP3A4 (intensity 80). Derived: Triazolam exposure lowered.
Inferred via Enzyme:CYP3A4 (exposure lowered)
Rate this interaction. Reports are anonymous and help curate the page.
Clinical relevance: does this interaction matter in practice?trivialcritical
Confidence in this inference: is the inferred magnitude sound?overstatedsound
Mechanism description, if it needs work:
Is this row worth surfacing?
Your own experience with this combination:
Experience (1 a little, 5 a lot)
Outcome (-100 worst, +100 best)
Verapamil inhibits CYP3A4 (inhibitor_moderate, intensity 55); Triazolam is a substrate_major of CYP3A4 (intensity 80). Derived: Triazolam exposure raised.
Inferred via Enzyme:CYP3A4 (exposure raised)
Rate this interaction. Reports are anonymous and help curate the page.
Clinical relevance: does this interaction matter in practice?trivialcritical
Confidence in this inference: is the inferred magnitude sound?overstatedsound
Mechanism description, if it needs work:
Is this row worth surfacing?
Your own experience with this combination:
Experience (1 a little, 5 a lot)
Outcome (-100 worst, +100 best)
Erythromycin inhibits CYP3A4 (inhibitor_moderate, intensity 55); Triazolam is a substrate_major of CYP3A4 (intensity 80). Derived: Triazolam exposure raised.
Inferred via Enzyme:CYP3A4 (exposure raised)
Rate this interaction. Reports are anonymous and help curate the page.
Clinical relevance: does this interaction matter in practice?trivialcritical
Confidence in this inference: is the inferred magnitude sound?overstatedsound
Mechanism description, if it needs work:
Is this row worth surfacing?
Your own experience with this combination:
Experience (1 a little, 5 a lot)
Outcome (-100 worst, +100 best)
Fluconazole inhibits CYP3A4 (inhibitor_moderate, intensity 55); Triazolam is a substrate_major of CYP3A4 (intensity 80). Derived: Triazolam exposure raised.
Inferred via Enzyme:CYP3A4 (exposure raised)
Rate this interaction. Reports are anonymous and help curate the page.
Clinical relevance: does this interaction matter in practice?trivialcritical
Confidence in this inference: is the inferred magnitude sound?overstatedsound
Mechanism description, if it needs work:
Is this row worth surfacing?
Your own experience with this combination:
Experience (1 a little, 5 a lot)
Outcome (-100 worst, +100 best)
Patient experience
No patient-experience reports yet.
Relevant anecdote
No anecdotes yet. Share a relevant one.
Relevant Literature
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Summary
Classes
Benzodiazepine, Sedative-Hypnotic
Common uses
Pharmacy
Pharmacology
Purported mechanism
GABAA positive allosteric modulator