Mixed amphetamine salts: Difference between revisions
From Pharmacopedia
More actions
| [checked revision] | [checked revision] |
MDElliottMD (talk | contribs) No edit summary |
MDElliottMD (talk | contribs) No edit summary |
||
| Line 31: | Line 31: | ||
The net result is a robust increase in synaptic dopamine and norepinephrine in prefrontal cortex, striatum, and nucleus accumbens — underlying both therapeutic (attention, executive function, wakefulness) and reinforcing (euphoria, abuse liability) effects. | The net result is a robust increase in synaptic dopamine and norepinephrine in prefrontal cortex, striatum, and nucleus accumbens — underlying both therapeutic (attention, executive function, wakefulness) and reinforcing (euphoria, abuse liability) effects. | ||
| indications = | | indications = <indication slug="adhd" title="ADHD in children, adolescents, and adults" author="MDElliottMD"/> | ||
<indication slug="narcolepsy" title="Narcolepsy" author="MDElliottMD"/> | |||
<indication slug="trd-augment" title="Treatment-resistant depression (augmentation)" author="MDElliottMD"> | |||
Off-label. | |||
</indication> | |||
<indication slug="shift-work" title="Excessive daytime sleepiness in shift-work disorder" author="MDElliottMD"> | |||
Off-label. | |||
</indication> | |||
<indication slug="chronic-illness-cog" title="Cognitive symptoms in chronic illness" author="MDElliottMD"> | |||
Off-label. | |||
</indication> | |||
| dosing = <titration slug="typical-adult" title="Typical Adult" author="MDElliottMD"> | | dosing = <titration slug="typical-adult" title="Typical Adult" author="MDElliottMD"> | ||
Start at 5 mg XR; may increase by 5 mg each day until the desired effect is reached, up to 30 mg XR to start, and up to 60 mg XR eventually if necessary, in 10 mg increments. | Start at 5 mg XR; may increase by 5 mg each day until the desired effect is reached, up to 30 mg XR to start, and up to 60 mg XR eventually if necessary, in 10 mg increments. | ||