Atropa belladonna: Difference between revisions
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| routes = Oral, topical | | routes = Oral, topical | ||
| mechanism = Tropane alkaloids: hyoscyamine (dominant; the racemic form is atropine), scopolamine. Competitive muscarinic antagonism. | | mechanism = Tropane alkaloids: hyoscyamine (dominant; the racemic form is atropine), scopolamine. Competitive muscarinic antagonism. | ||
| intro = ''Atropa belladonna'' is the deadly nightshade of European herbal tradition | | intro = ''Atropa belladonna'' is the deadly nightshade of European herbal tradition, a Solanaceae perennial with shiny black berries deceptively similar to currants. Named for [[wiki:Atropos|Atropos]], the Fate who cuts the thread, and ''bella donna'' ("beautiful woman") because Renaissance Italian women instilled the juice into their eyes to dilate the pupils. Long history in witchcraft (flying ointments), poisoning, and modern ophthalmology (atropine). | ||
| legal = Plant unrestricted; pharmaceutical atropine Rx-only | | legal = Plant unrestricted; pharmaceutical atropine Rx-only | ||
| seealso = [[Datura]], [[Brugmansia]], [[Mandragora]], [[Hyoscyamus niger]] | | seealso = [[Datura]], [[Brugmansia]], [[Mandragora]], [[Hyoscyamus niger]] | ||