Bufo alvarius

Animal Medicine, Phantastica

Bufo alvarius

Sonoran Desert Toad, Colorado River Toad

Bufo alvarius is the only toad whose parotid-gland venom contains 5-MeO-DMT in psychoactively significant quantities. (The cane toad, Bufo marinus, has bufotenine and cardiotoxic bufosteroids instead.) Native to the Sonoran Desert. The dried venom ("toad smoke") is one of the most powerful entheogens known, onset in seconds, full peak in ~5 min, baseline restored within 15.

Experience

👥 No personal reports yet

⚕ No clinical reports yet

Log in to add your own experience.

Problems

No problems yet. Be the first to suggest one.

+ Add a problem

Titration strategies

No titration strategies yet. Be the first to suggest one.

+ Add a titration strategy

Effects

No effects listed yet. Be the first to suggest one.

+ Add an effect

Relevant anecdote

No anecdotes yet. Share a relevant one.

+ Add an anecdote

Relevant Literature

No literature entries yet.

Log in to submit relevant literature.

See also

5-MeO-DMT, DMT, Anadenanthera

References

Summary

Classes

Animal Medicine, Phantastica

Common uses

Visionary▲0▼

Pharmacy

Preparations

Parotid-gland venom expressed onto a glass plate, dried into a shellac-like resin, vaporized and inhaled

Pharmacology

Routes

Inhalation (vaporized)

Onset

Seconds

Duration

~15 min

Legal status

5-MeO-DMT is Schedule I in US (since 2011); the toad itself is protected in several southwestern states

Purported mechanism

5-MeO-DMT is a potent 5-HT1A agonist (greater than 5-HT2A). Distinct from N,N-DMT in producing a more unitive, less visual, often ego-dissolving experience.

“Pendell's corner

I wasn't looking forward to this. I'm not looking forward to this. I was tired. "Again?" I thought, "another ally?" I've never been big on the dating scene, but meeting an ally isn't even like dating, it's like dating with a trial marriage. You have to give yourself over to it.

— Dale Pendell, Pharmako/Gnosis, p. 217