Enzyme:NUDT15: Difference between revisions
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MDElliottMD (talk | contribs) m MDElliottMD moved page Pharmacopedia:Pharmacogenomics sandbox/Enzyme NUDT15 to Enzyme:NUDT15: Migrate enzyme entity pages from Pharmacogenomics sandbox to the new Enzyme: namespace |
MDElliottMD (talk | contribs) Add scope="col" to the data-table column headers for screen-reader association (ADA audit M5; designer-claude 2026-05-22) |
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{| class="wikitable sortable" style="width:100%;" | {| class="wikitable sortable" style="width:100%;" | ||
! Medicine !! Therapeutic class !! NUDT15 relevance !! Clinical notes | ! scope="col" | Medicine !! scope="col" | Therapeutic class !! scope="col" | NUDT15 relevance !! scope="col" | Clinical notes | ||
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| '''[[Azathioprine]]''' || Immunosuppressant (IBD, transplant, autoimmune disease) || major || Prodrug of mercaptopurine; the mercaptopurine pharmacology applies after conversion. NUDT15-deficiency myelosuppression risk is the same as for mercaptopurine. FDA labeling references NUDT15 (and TPMT) testing. | | '''[[Azathioprine]]''' || Immunosuppressant (IBD, transplant, autoimmune disease) || major || Prodrug of mercaptopurine; the mercaptopurine pharmacology applies after conversion. NUDT15-deficiency myelosuppression risk is the same as for mercaptopurine. FDA labeling references NUDT15 (and TPMT) testing. | ||