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Pimozide: Difference between revisions

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Revision as of 03:31, 14 May 2026

Antipsychotic, Neuroleptic
Pimozide
Orap

Experience

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Problems

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Titration strategies

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Effects

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Interactions

Pharmacogenomic + mechanism interactions2 edges
Pharmacogenomic guideline recommendationsCPIC and Dutch Pharmacogenetics Working Group clinical guidelines
Phenotype:CYP2D6 poor metabolizer dose reduce 50 DPWG 60 / 100
DPWG guideline: Patients who are CYP2D6 intermediate metabolizers should be given no more than 80% of the standard maximum dose of pimozide while patients who are CYP2D6 poor metabolizers should be given no more than 50% of the standard maximum dose.
Phenotype:CYP2D6 intermediate metabolizer dose reduce 50 DPWG 60 / 100
DPWG guideline: Patients who are CYP2D6 intermediate metabolizers should be given no more than 80% of the standard maximum dose of pimozide while patients who are CYP2D6 poor metabolizers should be given no more than 50% of the standard maximum dose.

Patient experience

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Summary
Classes
Antipsychotic, Neuroleptic
Common uses
Pharmacy
Pharmacology
Purported mechanism
Diphenylbutylpiperidine D2 antagonist