Coffee: Difference between revisions

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Plant Medicine, Excitantia, Caffeine plant, Xanthine

Coffee

Coffea arabica, Coffea canephora (robusta)

Coffee is the seed of the Coffea genus (Rubiaceae — the same family as Cinchona/quinine and DMT-bearing Psychotria viridis). C. arabica (0.6–1.6% caffeine) is a tetraploid cultigen originating in the Ethiopian highlands; C. canephora (robusta, 1.2–3.2% caffeine) has more caffeine and less flavor. First popularized in Yemen by Sufi monks for sustaining night-long prayer.

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References

Summary

Classes

Plant Medicine, Excitantia, Caffeine plant, Xanthine

Common uses

Alertness0, Fatigue0, Caffeine source0

Pharmacy

Starting dose

One cup (~80–145 mg caffeine for brewed; 60–100 mg for instant)

Preparations

Roasted beans, ground; brewed (drip, French press, espresso, cold brew, percolated)

Pharmacology

Routes

Oral

Onset

~15–30 min

Duration

3–5 h (subjective)

Half-life

~5 h (caffeine)

Bioavailability

~99% (caffeine)

Pregnancy

Limit to <200 mg/d (~2 cups brewed)

Legal status

Unrestricted (food)

Purported mechanism

Caffeine is a non-selective adenosine A1/A2A receptor antagonist; also weak PDE inhibition. Beans contain theobromine (3,7-DMX) and theophylline (1,3-DMX) in smaller amounts.

“Pendell's corner

Stimulants were the perfect drugs for capitalism. They substituted for food. They were the mill to squeeze time out of the body, and the clocks were the scales on which to weigh it.

— Dale Pendell, Pharmako/Dynamis

@@ Line 20: / Line 20: @@
 {{PendellsCorner
-| quote  = Coffee is the alkaloid of capitalism, the wakefulness of the office and the assembly line, the small bitter cup that built the bourgeois soul. She is also the muse of philosophers, of journalists, of the late-night letter &mdash; plural, the most domesticated of the wakeful Allies, and the one that has shaped, more than any other plant in the modern era, the rhythm of how we work and how we dream.
+| quote  = Stimulants were the perfect drugs for capitalism. They substituted for food. They were the mill to squeeze time out of the body, and the clocks were the scales on which to weigh it.
 | volume = Dynamis
-| voice  = curated paraphrase &mdash; replace with verbatim passage
 }}